Receptors, Purinergic P2X7
"Receptors, Purinergic P2X7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purinergic P2X neurotransmitter receptor that plays a role in pain sensation signaling and regulation of inflammatory processes.
Descriptor ID |
D058486
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MeSH Number(s) |
D12.776.157.530.400.400.750.700 D12.776.543.550.450.500.600.700 D12.776.543.585.400.500.600.700 D12.776.543.750.695.700.720.250.700 D12.776.543.750.720.700.720.500.700
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Concept/Terms |
Receptors, Purinergic P2X7- Receptors, Purinergic P2X7
- P2X7 Receptors, Purinergic
- Purinergic P2X7 Receptors
- P2X7 Receptor
- P2X7 Purinoceptor
- Purinoceptor, P2X7
- P2Z Receptor
- Purinoceptor P2Z
- P2Z, Purinoceptor
- P2X7 Purinoceptors
- Purinoceptors, P2X7
- Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7
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Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2X7".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
- Receptors, Purinergic P2X7 [D12.776.157.530.400.400.750.700]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Receptors, Purinergic P2X [D12.776.543.550.450.500.600]
- Receptors, Purinergic P2X7 [D12.776.543.550.450.500.600.700]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
- Receptors, Purinergic P2X7 [D12.776.543.585.400.500.600.700]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.695.700.720.250]
- Receptors, Purinergic P2X7 [D12.776.543.750.695.700.720.250.700]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
- Receptors, Purinergic P2X7 [D12.776.543.750.720.700.720.500.700]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2X7".
This graph shows the total number of publications written about "Receptors, Purinergic P2X7" by people in this website by year, and whether "Receptors, Purinergic P2X7" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 | 2007 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2012 | 1 | 0 | 1 | 2013 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2023 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Purinergic P2X7" by people in Profiles.
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Huang Q, Ying J, Yu W, Dong Y, Xiong H, Zhang Y, Liu J, Wang X, Hua F. P2X7 Receptor: an Emerging Target in Alzheimer's Disease. Mol Neurobiol. 2024 May; 61(5):2866-2880.
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Zorina-Lichtenwalter K, Ase AR, Verma V, Parra AIM, Komarova S, Khadra A, S?gu?la P, Diatchenko L. Characterization of Common Genetic Variants in P2RX7 and Their Contribution to Chronic Pain Conditions. J Pain. 2024 Feb; 25(2):545-556.
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Grace PM, Strand KA, Galer EL, Rice KC, Maier SF, Watkins LR. Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats. Brain Behav Immun. 2018 08; 72:45-50.
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Carta S, Penco F, Lavieri R, Martini A, Dinarello CA, Gattorno M, Rubartelli A. Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):2835-40.
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Joosten LA, Netea MG, Dinarello CA. Interleukin-1? in innate inflammation, autophagy and immunity. Semin Immunol. 2013 Dec 15; 25(6):416-24.
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Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013 Jan 01; 187(1):28-33.
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Lorca RA, Rozas C, Loyola S, Moreira-Ramos S, Zeise ML, Kirkwood A, Huidobro-Toro JP, Morales B. Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region. Eur J Neurosci. 2011 Apr; 33(7):1175-1185.
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Gomes DA, Song Z, Stevens W, Sladek CD. Sustained stimulation of vasopressin and oxytocin release by ATP and phenylephrine requires recruitment of desensitization-resistant P2X purinergic receptors. Am J Physiol Regul Integr Comp Physiol. 2009 Oct; 297(4):R940-9.
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Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Gr?ne HJ, Schaefer L. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem. 2009 Sep 04; 284(36):24035-48.
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Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol. 2009; 27:519-50.
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