 Receptors, Purinergic P2X3
"Receptors, Purinergic P2X3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension, and NEUROPATHIC PAIN. The receptor comprises three P2X3 subunits. The P2X3 subunits are also associated with P2X2 RECEPTOR subunits in a heterotrimeric receptor variant.
| Descriptor ID |
D058477
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| MeSH Number(s) |
D12.776.157.530.400.400.750.300 D12.776.543.550.450.500.600.300 D12.776.543.585.400.500.600.300 D12.776.543.750.695.700.720.250.300 D12.776.543.750.720.700.720.500.300
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| Concept/Terms |
Receptors, Purinergic P2X3- Receptors, Purinergic P2X3
- P2X3 Receptors, Purinergic
- Purinergic P2X3 Receptors
- P2X3 Receptor
- Receptor, P2X3
- Purinergic Receptor P2X, Ligand-Gated Ion Channel, 3
- P2X3 Purinoceptor
- Purinoceptor, P2X3
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Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2X3".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
- Receptors, Purinergic P2X3 [D12.776.157.530.400.400.750.300]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Receptors, Purinergic P2X [D12.776.543.550.450.500.600]
- Receptors, Purinergic P2X3 [D12.776.543.550.450.500.600.300]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
- Receptors, Purinergic P2X3 [D12.776.543.585.400.500.600.300]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.695.700.720.250]
- Receptors, Purinergic P2X3 [D12.776.543.750.695.700.720.250.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
- Receptors, Purinergic P2X3 [D12.776.543.750.720.700.720.500.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2X3".
This graph shows the total number of publications written about "Receptors, Purinergic P2X3" by people in this website by year, and whether "Receptors, Purinergic P2X3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Purinergic P2X3" by people in Profiles.
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Andres-Hernando A, Kuwabara M, Orlicky DJ, Vandenbeuch A, Cicerchi C, Kinnamon SC, Finger TE, Johnson RJ, Lanaspa MA. Sugar causes obesity and metabolic syndrome in mice independently of sweet taste. Am J Physiol Endocrinol Metab. 2020 08 01; 319(2):E276-E290.
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Drummond PD, Morellini N, Finch PM, Birklein F, Knudsen LF. Complex regional pain syndrome: intradermal injection of phenylephrine evokes pain and hyperalgesia in a subgroup of patients with upregulated a1-adrenoceptors on dermal nerves. Pain. 2018 Nov; 159(11):2296-2305.
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Larson ED, Vandenbeuch A, Voigt A, Meyerhof W, Kinnamon SC, Finger TE. The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. J Neurosci. 2015 Dec 02; 35(48):15984-95.
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Todorovic SM. Is Diabetic Nerve Pain Caused by Dysregulated Ion Channels in Sensory Neurons? Diabetes. 2015 Dec; 64(12):3987-9.
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Vandenbeuch A, Larson ED, Anderson CB, Smith SA, Ford AP, Finger TE, Kinnamon SC. Postsynaptic P2X3-containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice. J Physiol. 2015 Mar 01; 593(5):1113-25.
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Ohkuri T, Horio N, Stratford JM, Finger TE, Ninomiya Y. Residual chemoresponsiveness to acids in the superior laryngeal nerve in "taste-blind" (P2X2/P2X3 double-KO) mice. Chem Senses. 2012 Jul; 37(6):523-32.
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Hallock RM, Tatangelo M, Barrows J, Finger TE. Residual chemosensory capabilities in double P2X2/P2X3 purinergic receptor null mice: intraoral or postingestive detection? Chem Senses. 2009 Nov; 34(9):799-808.
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Eddy MC, Eschle BK, Barrows J, Hallock RM, Finger TE, Delay ER. Double P2X2/P2X3 purinergic receptor knockout mice do not taste NaCl or the artificial sweetener SC45647. Chem Senses. 2009 Nov; 34(9):789-97.
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Gomes DA, Song Z, Stevens W, Sladek CD. Sustained stimulation of vasopressin and oxytocin release by ATP and phenylephrine requires recruitment of desensitization-resistant P2X purinergic receptors. Am J Physiol Regul Integr Comp Physiol. 2009 Oct; 297(4):R940-9.
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Finger TE, Danilova V, Barrows J, Bartel DL, Vigers AJ, Stone L, Hellekant G, Kinnamon SC. ATP signaling is crucial for communication from taste buds to gustatory nerves. Science. 2005 Dec 02; 310(5753):1495-9.
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