 Receptors, Purinergic P2X2
"Receptors, Purinergic P2X2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension and NEUROPATHIC PAIN. The receptor comprises three P2X2 subunits. The P2X2 subunits also have been found associated with P2X3 RECEPTOR subunits in a heterotrimeric receptor variant.
| Descriptor ID |
D058476
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| MeSH Number(s) |
D12.776.157.530.400.400.750.200 D12.776.543.550.450.500.600.200 D12.776.543.585.400.500.600.200 D12.776.543.750.695.700.720.250.200 D12.776.543.750.720.700.720.500.200
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| Concept/Terms |
Receptors, Purinergic P2X2- Receptors, Purinergic P2X2
- P2X2 Receptors, Purinergic
- Purinergic P2X2 Receptors
- P2X2 Purinoceptor
- Purinoceptor, P2X2
- Purinergic Receptor P2X, Ligand-Gated Ion Channel, 2
- P2X2 Purinoceptors
- Purinoceptors, P2X2
- P2X2 Receptor
- Receptor, P2X2
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Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2X2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
- Receptors, Purinergic P2X2 [D12.776.157.530.400.400.750.200]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Receptors, Purinergic P2X [D12.776.543.550.450.500.600]
- Receptors, Purinergic P2X2 [D12.776.543.550.450.500.600.200]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
- Receptors, Purinergic P2X2 [D12.776.543.585.400.500.600.200]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.695.700.720.250]
- Receptors, Purinergic P2X2 [D12.776.543.750.695.700.720.250.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
- Receptors, Purinergic P2X2 [D12.776.543.750.720.700.720.500.200]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2X2".
This graph shows the total number of publications written about "Receptors, Purinergic P2X2" by people in this website by year, and whether "Receptors, Purinergic P2X2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Purinergic P2X2" by people in Profiles.
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Andres-Hernando A, Kuwabara M, Orlicky DJ, Vandenbeuch A, Cicerchi C, Kinnamon SC, Finger TE, Johnson RJ, Lanaspa MA. Sugar causes obesity and metabolic syndrome in mice independently of sweet taste. Am J Physiol Endocrinol Metab. 2020 08 01; 319(2):E276-E290.
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Yang R, Montoya A, Bond A, Walton J, Kinnamon JC. Immunocytochemical analysis of P2X2 in rat circumvallate taste buds. BMC Neurosci. 2012 May 23; 13:51.
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Ohkuri T, Horio N, Stratford JM, Finger TE, Ninomiya Y. Residual chemoresponsiveness to acids in the superior laryngeal nerve in "taste-blind" (P2X2/P2X3 double-KO) mice. Chem Senses. 2012 Jul; 37(6):523-32.
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Huang YA, Stone LM, Pereira E, Yang R, Kinnamon JC, Dvoryanchikov G, Chaudhari N, Finger TE, Kinnamon SC, Roper SD. Knocking out P2X receptors reduces transmitter secretion in taste buds. J Neurosci. 2011 Sep 21; 31(38):13654-61.
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Vandenbeuch A, Tizzano M, Anderson CB, Stone LM, Goldberg D, Kinnamon SC. Evidence for a role of glutamate as an efferent transmitter in taste buds. BMC Neurosci. 2010 Jun 21; 11:77.
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Hallock RM, Tatangelo M, Barrows J, Finger TE. Residual chemosensory capabilities in double P2X2/P2X3 purinergic receptor null mice: intraoral or postingestive detection? Chem Senses. 2009 Nov; 34(9):799-808.
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Eddy MC, Eschle BK, Barrows J, Hallock RM, Finger TE, Delay ER. Double P2X2/P2X3 purinergic receptor knockout mice do not taste NaCl or the artificial sweetener SC45647. Chem Senses. 2009 Nov; 34(9):789-97.
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Gomes DA, Song Z, Stevens W, Sladek CD. Sustained stimulation of vasopressin and oxytocin release by ATP and phenylephrine requires recruitment of desensitization-resistant P2X purinergic receptors. Am J Physiol Regul Integr Comp Physiol. 2009 Oct; 297(4):R940-9.
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Finger TE, Danilova V, Barrows J, Bartel DL, Vigers AJ, Stone L, Hellekant G, Kinnamon SC. ATP signaling is crucial for communication from taste buds to gustatory nerves. Science. 2005 Dec 02; 310(5753):1495-9.
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Lorca RA, Coddou C, Gazit?a MC, Bull P, Arredondo C, Huidobro-Toro JP. Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulation. J Neurochem. 2005 Oct; 95(2):499-512.
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