 Pulmonary Fibrosis
"Pulmonary Fibrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Descriptor ID |
D011658
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| MeSH Number(s) |
C08.381.765
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| Concept/Terms |
Pulmonary Fibrosis- Pulmonary Fibrosis
- Pulmonary Fibroses
- Fibroses, Pulmonary
- Fibrosis, Pulmonary
Alveolitis, Fibrosing- Alveolitis, Fibrosing
- Alveolitides, Fibrosing
- Fibrosing Alveolitides
- Fibrosing Alveolitis
- Hamman-Rich Syndrome
- Hamman Rich Syndrome
- Syndrome, Hamman-Rich
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Below are MeSH descriptors whose meaning is more general than "Pulmonary Fibrosis".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Fibrosis".
This graph shows the total number of publications written about "Pulmonary Fibrosis" by people in this website by year, and whether "Pulmonary Fibrosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 3 | 0 | 3 | | 1998 | 2 | 1 | 3 | | 2000 | 2 | 0 | 2 | | 2001 | 2 | 1 | 3 | | 2002 | 8 | 1 | 9 | | 2003 | 3 | 0 | 3 | | 2004 | 5 | 1 | 6 | | 2005 | 12 | 0 | 12 | | 2006 | 3 | 4 | 7 | | 2007 | 12 | 3 | 15 | | 2008 | 9 | 1 | 10 | | 2009 | 7 | 0 | 7 | | 2010 | 4 | 1 | 5 | | 2011 | 8 | 1 | 9 | | 2012 | 8 | 1 | 9 | | 2013 | 2 | 3 | 5 | | 2014 | 7 | 1 | 8 | | 2015 | 4 | 0 | 4 | | 2016 | 4 | 5 | 9 | | 2017 | 10 | 3 | 13 | | 2018 | 6 | 0 | 6 | | 2019 | 7 | 3 | 10 | | 2020 | 7 | 1 | 8 | | 2021 | 5 | 1 | 6 | | 2022 | 6 | 0 | 6 | | 2023 | 9 | 0 | 9 | | 2024 | 12 | 4 | 16 | | 2025 | 10 | 1 | 11 | | 2026 | 4 | 0 | 4 |
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Below are the most recent publications written about "Pulmonary Fibrosis" by people in Profiles.
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Cooley JC, Penick SK, Wilson JA, Javkhlan N, Foster DG, Edelman BL, Schott CA, Humphries SM, Lynch DA, Schwartz DA, Riches DWH, Redente EF. Nintedanib increases BCL-2 in fibrotic fibroblasts, enhancing ABT-199 apoptosis and fibrosis resolution. Am J Respir Cell Mol Biol. 2026 Aug 01; 74(8):1103-1113.
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Foster DG, Javkhlan N, Black BP, Vestal BE, Riches DW, Redente EF. Pulmonary fibroblast subsets demonstrate differentially enriched signaling pathways during fibrosis resolution and repair. JCI Insight. 2026 Jul 08; 11(13).
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Yadav R, Lippitt WL, Chae KJ, Rieck J, Carlson NE, Liao SY, Mroz MM, Barkes B, Humphries SM, Oh A, Hwang HJ, Parker K, Fuentealba AI, McLaren T, Marrocchio C, Fingerlin TE, Culver DA, Lynch DA, Maier LA. Demographic and Physiological Differences Between Fibrotic and Nonfibrotic CT Subtypes of Sarcoidosis. Chest. 2026 Jul; 170(1):137-148.
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Christian L, Yilmaz H, Ruwisch J, Giercke L, Seeliger B, Kamp JC, Bayraktar S, Ewen R, Graalmann T, Fuge J, Greer M, Ius F, Welte T, Liao SY, Yang IV, Hohlfeld JM, Hoeper MM, Gottlieb J, Kaminski N, Prasse A, Jonigk D, Li Y, Falk C, Neubert L, Schupp JC. Spatial transcriptomics uncovers hybrid, proinflammatory, and profibrotic cellular niches in pulmonary granuloma of patients with chronic sarcoidosis. Am J Respir Crit Care Med. 2026 02 01; 212(2):338-350.
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Murthy A, Rodríguez LR, Roque Barboza W, Tomer Y, Bui S, Carson P, Dimopoulos T, Iyer S, Chavez K, Cooper CH, Katzen JB, Beers MF. Regulatory T cells protect against aberrant remodeling in a mouse model of pulmonary fibrosis. Mucosal Immunol. 2026 Apr; 19(2):1769-1782.
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Signoretti C, Fatehi S, Drewes R, Cendali F, Dzieciatkowska M, D'Alessandro A, Bae Y, Gupte SA. Bleomycin-induced lung fibrosis and dysfunction is exacerbated by G6PD deficiency. Am J Physiol Lung Cell Mol Physiol. 2026 02 01; 330(2):L145-L158.
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Schott CA, Redente EF. Pathogenic expansion: fibroblast proliferation fuels fibrosis. J Clin Invest. 2025 11 17; 135(22).
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Freeberg MAT, Redente EF, Perelas A, Riches DWH, Schwartz DA, Sime PJ. Pulmonary Fibrosis-Focusing on the Future: Aspen Lung Conference 2024 Summary. Am J Respir Cell Mol Biol. 2025 11; 73(5):653-667.
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Koslow M, Baraghoshi D, Swigris JJ, Brown KK, Fernández Pérez ER, Huie TJ, Keith RC, Mohning MP, Solomon JJ, Yunt ZX, Manco G, Lynch DA, Humphries SM. One-Year Change in Quantitative Computed Tomography Is Associated with Meaningful Outcomes in Fibrotic Lung Disease. Am J Respir Crit Care Med. 2025 10; 211(10):1775-1784.
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Hena KM, Barkes B, Heinrich F, Kogan R, Strykowski RK, Obi ON, Judson MA, Maier LA, Patterson KC. An Inventory of Clinical Sarcoidosis Status in the United States. Chest. 2026 Jan; 169(1):159-173.
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