 Iron Regulatory Protein 2
"Iron Regulatory Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.
| Descriptor ID |
D035942
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| MeSH Number(s) |
D08.811.520.241.300.050.750 D12.776.157.427.374.375.961 D12.776.157.725.437 D12.776.494.750 D12.776.556.579.374.375.962 D12.776.664.962.437
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| Concept/Terms |
Iron Regulatory Protein 2- Iron Regulatory Protein 2
- IRP-2 RNA-binding protein
- IRP 2 RNA binding protein
- RNA-binding protein, IRP-2
- IREB2 Protein
- IRP2 Protein
- Iron-Responsive-Element Binding Protein 2
- IRE-BP2
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Below are MeSH descriptors whose meaning is more general than "Iron Regulatory Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Iron Regulatory Protein 2".
This graph shows the total number of publications written about "Iron Regulatory Protein 2" by people in this website by year, and whether "Iron Regulatory Protein 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 2 | 2 | | 2015 | 1 | 1 | 2 |
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Below are the most recent publications written about "Iron Regulatory Protein 2" by people in Profiles.
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Cho MH, Castaldi PJ, Hersh CP, Hobbs BD, Barr RG, Tal-Singer R, Bakke P, Gulsvik A, San Jos? Est?par R, Van Beek EJ, Coxson HO, Lynch DA, Washko GR, Laird NM, Crapo JD, Beaty TH, Silverman EK. A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):559-69.
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Lee JH, Cho MH, Hersh CP, McDonald ML, Wells JM, Dransfield MT, Bowler RP, Lynch DA, Lomas DA, Crapo JD, Silverman EK. IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2015 Mar; 52(3):365-76.
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DeRuisseau KC, Park YM, DeRuisseau LR, Cowley PM, Fazen CH, Doyle RP. Aging-related changes in the iron status of skeletal muscle. Exp Gerontol. 2013 Nov; 48(11):1294-302.
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Ghosh MC, Zhang DL, Jeong SY, Kovtunovych G, Ollivierre-Wilson H, Noguchi A, Tu T, Senecal T, Robinson G, Crooks DR, Tong WH, Ramaswamy K, Singh A, Graham BB, Tuder RM, Yu ZX, Eckhaus M, Lee J, Springer DA, Rouault TA. Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2a. Cell Metab. 2013 Feb 05; 17(2):271-81.
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Siedlinski M, Tingley D, Lipman PJ, Cho MH, Litonjua AA, Sparrow D, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Lange C, Silverman EK. Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. Hum Genet. 2013 Apr; 132(4):431-41.
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