Coproporphyrinogen Oxidase
"Coproporphyrinogen Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.
| Descriptor ID |
D003304
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| MeSH Number(s) |
D08.811.682.660.250
|
| Concept/Terms |
Coproporphyrinogen Oxidase- Coproporphyrinogen Oxidase
- Oxidase, Coproporphyrinogen
- Coproporphyrinogen III Oxidases
- III Oxidases, Coproporphyrinogen
- Oxidases, Coproporphyrinogen III
- Coproporphyrinogenase
|
Below are MeSH descriptors whose meaning is more general than "Coproporphyrinogen Oxidase".
Below are MeSH descriptors whose meaning is more specific than "Coproporphyrinogen Oxidase".
This graph shows the total number of publications written about "Coproporphyrinogen Oxidase" by people in this website by year, and whether "Coproporphyrinogen Oxidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Coproporphyrinogen Oxidase" by people in Profiles.
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Cooper CL, Stob CM, Jones MA, Lash TD. Metabolism of pentacarboxylate porphyrinogens by highly purified human coproporphyrinogen oxidase: further evidence for the existence of an abnormal pathway for heme biosynthesis. Bioorg Med Chem. 2005 Nov 15; 13(22):6244-51.
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Jones MA, Taneja M, Xu Y, Chung W, Stob CM, Lash TD. An effective chromatographic separation of chicken red blood cell coproporphyrinogen oxidase and uroporphyrinogen decarboxylase, two enzymes in heme biosynthesis. Bioorg Med Chem Lett. 2004 Nov 15; 14(22):5559-64.