 Transcription Initiation, Genetic
"Transcription Initiation, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process that starts the transcription of an RNA molecule. It includes the assembly of the initiation complex and establishment of the start site.
| Descriptor ID |
D061785
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| MeSH Number(s) |
G02.111.873.625 G05.297.700.625
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Initiation, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Transcription Initiation, Genetic".
This graph shows the total number of publications written about "Transcription Initiation, Genetic" by people in this website by year, and whether "Transcription Initiation, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2021 | 1 | 1 | 2 | | 2024 | 0 | 1 | 1 | | 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Transcription Initiation, Genetic" by people in Profiles.
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Nagel M, Taatjes DJ. Regulation of RNA polymerase II transcription through re-initiation and bursting. Mol Cell. 2025 May 15; 85(10):1907-1919.
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Stanley JT, Barone GEF, Townsend HA, Sigauke RF, Allen MA, Dowell RD. LIET model: capturing the kinetics of RNA polymerase from loading to termination. Nucleic Acids Res. 2025 Apr 10; 53(7).
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Leydon AR, Downing B, Solano Sanchez J, Loll-Krippleber R, Belliveau NM, Rodriguez-Mias RA, Bauer AJ, Watson IJ, Bae L, Vill?n J, Brown GW, Nemhauser JL. A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex. J Cell Biol. 2025 Feb 03; 224(2).
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Schier AC, Taatjes DJ. Everything at once: cryo-EM yields remarkable insights into human RNA polymerase II transcription. Nat Struct Mol Biol. 2021 07; 28(7):540-543.
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Tomko EJ, Luyties O, Rimel JK, Tsai CL, Fuss JO, Fishburn J, Hahn S, Tsutakawa SE, Taatjes DJ, Galburt EA. The Role of XPB/Ssl2 dsDNA Translocase Processivity in Transcription Start-site Scanning. J Mol Biol. 2021 07 09; 433(14):166813.
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Parida M, Nilson KA, Li M, Ball CB, Fuchs HA, Lawson CK, Luse DS, Meier JL, Price DH. Nucleotide Resolution Comparison of Transcription of Human Cytomegalovirus and Host Genomes Reveals Universal Use of RNA Polymerase II Elongation Control Driven by Dissimilar Core Promoter Elements. mBio. 2019 02 12; 10(1).
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Erickson B, Sheridan RM, Cortazar M, Bentley DL. Dynamic turnover of paused Pol II complexes at human promoters. Genes Dev. 2018 09 01; 32(17-18):1215-1225.
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Snijders Blok L, Hiatt SM, Bowling KM, Prokop JW, Engel KL, Cochran JN, Bebin EM, Bijlsma EK, Ruivenkamp CAL, Terhal P, Simon MEH, Smith R, Hurst JA, McLaughlin H, Person R, Crunk A, Wangler MF, Streff H, Symonds JD, Zuberi SM, Elliott KS, Sanders VR, Masunga A, Hopkin RJ, Dubbs HA, Ortiz-Gonzalez XR, Pfundt R, Brunner HG, Fisher SE, Kleefstra T, Cooper GM. De novo mutations in MED13, a component of the Mediator complex, are associated with a novel neurodevelopmental disorder. Hum Genet. 2018 May; 137(5):375-388.
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Gressel S, Schwalb B, Decker TM, Qin W, Leonhardt H, Eick D, Cramer P. CDK9-dependent RNA polymerase II pausing controls transcription initiation. Elife. 2017 10 10; 6.
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Alhadid Y, Chung S, Lerner E, Taatjes DJ, Borukhov S, Weiss S. Studying transcription initiation by RNA polymerase with diffusion-based single-molecule fluorescence. Protein Sci. 2017 Jul; 26(7):1278-1290.
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