 Ionophores
"Ionophores" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.
| Descriptor ID |
D007476
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| MeSH Number(s) |
D27.505.519.562.374 D27.720.395
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ionophores".
Below are MeSH descriptors whose meaning is more specific than "Ionophores".
This graph shows the total number of publications written about "Ionophores" by people in this website by year, and whether "Ionophores" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 3 | 4 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 3 | 3 | | 2009 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ionophores" by people in Profiles.
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Dailey AL, Greer MD, Sodia TZ, Jewell MP, Kalin TA, Cash KJ. LipiSensors: Exploiting Lipid Nanoemulsions to Fabricate Ionophore-Based Nanosensors. Biosensors (Basel). 2020 Sep 10; 10(9).
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Ding WQ, Lind SE. Metal ionophores - an emerging class of anticancer drugs. IUBMB Life. 2009 Nov; 61(11):1013-8.
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Lind SE, Park JS, Drexler JW. Pyrithione and 8-hydroxyquinolines transport lead across erythrocyte membranes. Transl Res. 2009 Sep; 154(3):153-9.
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Giannattasio G, Lai Y, Granata F, Mounier CM, Nallan L, Oslund R, Leslie CC, Marone G, Lambeau G, Gelb MH, Triggiani M. Expression of phospholipases A2 in primary human lung macrophages: role of cytosolic phospholipase A2-alpha in arachidonic acid release and platelet activating factor synthesis. Biochim Biophys Acta. 2009 Feb; 1791(2):92-102.
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Tucker DE, Gij?n MA, Spencer DM, Qiu ZH, Gelb MH, Leslie CC. Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages. J Leukoc Biol. 2008 Sep; 84(3):798-806.
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Perry C, Le H, Grichtchenko II. ANG II and calmodulin/CaMKII regulate surface expression and functional activity of NBCe1 via separate means. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F68-77.
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Ding WQ, Liu B, Vaught JL, Palmiter RD, Lind SE. Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells. Mol Cancer Ther. 2006 Jul; 5(7):1864-72.
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Gudz TI, Komuro H, Macklin WB. Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex. J Neurosci. 2006 Mar 01; 26(9):2458-66.
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Zarini S, Gij?n MA, Folco G, Murphy RC. Effect of arachidonic acid reacylation on leukotriene biosynthesis in human neutrophils stimulated with granulocyte-macrophage colony-stimulating factor and formyl-methionyl-leucyl-phenylalanine. J Biol Chem. 2006 Apr 14; 281(15):10134-42.
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Zemski Berry KA, Murphy RC. Analysis of polyunsaturated aminophospholipid molecular species using isotope-tagged derivatives and tandem mass spectrometry/mass spectrometry/mass spectrometry. Anal Biochem. 2006 Feb 01; 349(1):118-28.
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