Calcium Channel Agonists
"Calcium Channel Agonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.
Descriptor ID |
D002120
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MeSH Number(s) |
D27.505.519.562.124 D27.505.954.411.793.205
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Concept/Terms |
Calcium Channel Agonists- Calcium Channel Agonists
- Agonists, Calcium Channel
- Channel Agonists, Calcium
- Calcium Channel Activators
- Activators, Calcium Channel
- Channel Activators, Calcium
- Calcium Channel Agonist
- Agonist, Calcium Channel
- Channel Agonist, Calcium
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Below are MeSH descriptors whose meaning is more general than "Calcium Channel Agonists".
Below are MeSH descriptors whose meaning is more specific than "Calcium Channel Agonists".
This graph shows the total number of publications written about "Calcium Channel Agonists" by people in this website by year, and whether "Calcium Channel Agonists" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2010 | 0 | 2 | 2 | 2011 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Calcium Channel Agonists" by people in Profiles.
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Rubinstein J, Woo JG, Garcia AM, Alsaied T, Li J, Lunde PK, Moore RA, Laasmaa M, Sammons A, Mays WA, Miyamoto SD, Louch WE, Veldtman GR. Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis. Pediatr Cardiol. 2020 Dec; 41(8):1675-1688.
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Orfila JE, Shimizu K, Garske AK, Deng G, Maylie J, Traystman RJ, Quillinan N, Adelman JP, Herson PS. Increasing small conductance Ca2+-activated potassium channel activity reverses ischemia-induced impairment of long-term potentiation. Eur J Neurosci. 2014 Oct; 40(8):3179-88.
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Bannister RA, Beam KG. Impaired gating of an L-Type Ca(2+) channel carrying a mutation linked to malignant hyperthermia. Biophys J. 2013 May 07; 104(9):1917-22.
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Dabertrand F, Nelson MT, Brayden JE. Acidosis dilates brain parenchymal arterioles by conversion of calcium waves to sparks to activate BK channels. Circ Res. 2012 Jan 20; 110(2):285-94.
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Bannister RA, Beam KG. Properties of Na+ currents conducted by a skeletal muscle L-type Ca2+ channel pore mutant (SkEIIIK). Channels (Austin). 2011 May-Jun; 5(3):262-8.
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Est?ve E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, L?pez JR. A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR. J Gen Physiol. 2010 Jun; 135(6):619-28.
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Bannister RA, Est?ve E, Eltit JM, Pessah IN, Allen PD, L?pez JR, Beam KG. A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels. J Gen Physiol. 2010 Jun; 135(6):629-40.
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Chaurasia SS, Haque R, Pozdeyev N, Jackson CR, Iuvone PM. Temporal coupling of cyclic AMP and Ca/calmodulin-stimulated adenylyl cyclase to the circadian clock in chick retinal photoreceptor cells. J Neurochem. 2006 Nov; 99(4):1142-50.
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Rao A, Coan A, Welsh JE, Barclay WW, Koumenis C, Cramer SD. Vitamin D receptor and p21/WAF1 are targets of genistein and 1,25-dihydroxyvitamin D3 in human prostate cancer cells. Cancer Res. 2004 Mar 15; 64(6):2143-7.
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Chesnoy-Marchais D, Cathala L. Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons. Eur J Neurosci. 2001 Jun; 13(12):2195-204.
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