 Irritants
"Irritants" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.
| Descriptor ID |
D007509
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| MeSH Number(s) |
D27.720.400 D27.888.569.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Irritants".
Below are MeSH descriptors whose meaning is more specific than "Irritants".
This graph shows the total number of publications written about "Irritants" by people in this website by year, and whether "Irritants" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 | | 2020 | 0 | 2 | 2 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 2 | 2 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Irritants" by people in Profiles.
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Mishra N, Kant R, Kandhari K, Ammar DA, Tewari-Singh N, Pantcheva MB, Petrash JM, Agarwal C, Agarwal R. Nitrogen Mustard-Induced Ex Vivo Human Cornea Injury Model and Therapeutic Intervention by Dexamethasone. J Pharmacol Exp Ther. 2024 01 17; 388(2):484-494.
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Goswami DG, Singh SK, Okoyeocha EOM, Roney AK, Madadgar O, Tuttle R, Sosna W, Anantharam P, Croutch CR, Agarwal R, Tewari-Singh N. Dermal Exposure to Vesicating Nettle Agent Phosgene Oxime: Clinically Relevant Biomarkers and Skin Injury Progression in Murine Models. J Pharmacol Exp Ther. 2024 01 17; 388(2):536-545.
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Kandhari K, Kant R, Mishra N, Agarwal C, Agarwal R. Phenylarsine oxide induced corneal injury involves oxidative stress mediated unfolded protein response and ferroptotic cell death: Amelioration by NAC. Free Radic Biol Med. 2023 11 20; 209(Pt 2):265-281.
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Mishra N, Kant R, Goswami DG, Petrash JM, Agarwal C, Tewari-Singh N, Agarwal R. Metabolomics for identifying pathways involved in vesicating agent lewisite-induced corneal injury. Exp Eye Res. 2023 11; 236:109672.
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Mishra N, Agarwal R. Research models of sulfur mustard- and nitrogen mustard-induced ocular injuries and potential therapeutics. Exp Eye Res. 2022 10; 223:109209.
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Goswami DG, Mishra N, Kant R, Agarwal C, Ammar DA, Petrash JM, Tewari-Singh N, Agarwal R. Effect of dexamethasone treatment at variable therapeutic windows in reversing nitrogen mustard-induced corneal injuries in rabbit ocular in vivo model. Toxicol Appl Pharmacol. 2022 02 15; 437:115904.
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Presley CL, Militello M, Barber C, Ladd R, Laughter M, Ferguson H, Dewey J, Pulsipher KJ, Rundle CW, Dunnick CA. The History of Surfactants and Review of Their Allergic and Irritant Properties. Dermatitis. 2021 Sep-Oct 01; 32(5):289-297.
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Rundle CW, Presley CL, Militello M, Barber C, Powell DL, Jacob SE, Atwater AR, Watsky KL, Yu J, Dunnick CA. Hand hygiene during COVID-19: Recommendations from the American Contact Dermatitis Society. J Am Acad Dermatol. 2020 Dec; 83(6):1730-1737.
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Chung S, Baum CR, Nyquist AC. Chemical-Biological Terrorism and Its Impact on Children. Pediatrics. 2020 02; 145(2).
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Heller E, Murthy AS, Jen MV. A slime of the times: Two cases of acute irritant contact dermatitis from homemade slime. Pediatr Dermatol. 2019 Jan; 36(1):139-141.
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