 Tetrahydrofolates
"Tetrahydrofolates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds based on 5,6,7,8-tetrahydrofolate.
| Descriptor ID |
D013763
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| MeSH Number(s) |
D03.633.100.733.631.400.800 D08.211.840
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tetrahydrofolates".
Below are MeSH descriptors whose meaning is more specific than "Tetrahydrofolates".
This graph shows the total number of publications written about "Tetrahydrofolates" by people in this website by year, and whether "Tetrahydrofolates" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Tetrahydrofolates" by people in Profiles.
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Chen YY, Gupta MB, Grattton R, Powell TL, Jansson T. Down-regulation of placental folate transporters in intrauterine growth restriction. J Nutr Biochem. 2018 09; 59:136-141.
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Trausch JJ, Marcano-Vel?zquez JG, Matyjasik MM, Batey RT. Metal Ion-Mediated Nucleobase Recognition by the ZTP Riboswitch. Chem Biol. 2015 Jul 23; 22(7):829-37.
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Trausch JJ, Batey RT. A disconnect between high-affinity binding and efficient regulation by antifolates and purines in the tetrahydrofolate riboswitch. Chem Biol. 2014 Feb 20; 21(2):205-16.
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Brown MJ, Russo BC, O'Dee DM, Schmitt DM, Nau GJ. The contribution of the glycine cleavage system to the pathogenesis of Francisella tularensis. Microbes Infect. 2014 Apr; 16(4):300-9.
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Trausch JJ, Ceres P, Reyes FE, Batey RT. The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer. Structure. 2011 Oct 12; 19(10):1413-23.
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MacFarlane AJ, Liu X, Perry CA, Flodby P, Allen RH, Stabler SP, Stover PJ. Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice. J Biol Chem. 2008 Sep 19; 283(38):25846-53.
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Brody JR, Gallmeier E, Yoshimura K, Hucl T, Kulesza P, Canto MI, Hruban RH, Schulick RD, Kern SE. A proposed clinical test for monitoring fluoropyrimidine therapy: detection and stability of thymidylate synthase ternary complexes. Cancer Biol Ther. 2006 Aug; 5(8):923-7.
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Nakano E, Higgins JA, Powers HJ. Folate protects against oxidative modification of human LDL. Br J Nutr. 2001 Dec; 86(6):637-9.
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Thompson HR, Jones GM, Narkewicz MR. Ontogeny of hepatic enzymes involved in serine- and folate-dependent one-carbon metabolism in rabbits. Am J Physiol Gastrointest Liver Physiol. 2001 May; 280(5):G873-8.
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Selhub J, Seyoum E, Pomfret EA, Zeisel SH. Effects of choline deficiency and methotrexate treatment upon liver folate content and distribution. Cancer Res. 1991 Jan 01; 51(1):16-21.
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