 Folic Acid
"Folic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
| Descriptor ID |
D005492
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| MeSH Number(s) |
D03.633.100.733.631.400
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| Concept/Terms |
Folic Acid- Folic Acid
- Vitamin M
- Vitamin B9
- B9, Vitamin
- Pteroylglutamic Acid
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Below are MeSH descriptors whose meaning is more general than "Folic Acid".
Below are MeSH descriptors whose meaning is more specific than "Folic Acid".
This graph shows the total number of publications written about "Folic Acid" by people in this website by year, and whether "Folic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 2 | 1 | 3 | | 2002 | 2 | 5 | 7 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 2 | 3 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 2 | 3 | | 2007 | 0 | 2 | 2 | | 2008 | 4 | 1 | 5 | | 2009 | 1 | 3 | 4 | | 2010 | 0 | 3 | 3 | | 2011 | 5 | 3 | 8 | | 2012 | 3 | 4 | 7 | | 2013 | 2 | 3 | 5 | | 2014 | 1 | 2 | 3 | | 2015 | 2 | 2 | 4 | | 2016 | 5 | 2 | 7 | | 2017 | 6 | 3 | 9 | | 2018 | 2 | 5 | 7 | | 2019 | 1 | 3 | 4 | | 2020 | 3 | 0 | 3 | | 2021 | 3 | 4 | 7 | | 2022 | 0 | 2 | 2 | | 2023 | 2 | 3 | 5 | | 2024 | 1 | 3 | 4 | | 2025 | 3 | 2 | 5 | | 2026 | 2 | 0 | 2 |
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Below are the most recent publications written about "Folic Acid" by people in Profiles.
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Chakraborty J, Ghosh A, Awuah EB, Stabler SP, Field MS, Bailey RL, Stover PJ. Dietary folic acid prevents peripheral neuropathy in mouse models of neural tube defects and type 2 diabetes. Proc Natl Acad Sci U S A. 2026 Jan 06; 123(1):e2528095123.
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Swanson MA, Jiang H, Kolora LD, Molino R, Reisdorph R, Michel CR, Doenges KA, Leung KY, Lin X, Wong F, Lancaster S, Michael B, Snyder M, Hock DH, Stroud DA, Wood T, Binard R, Anderson-Lehman L, Christians U, Arning E, Friederich MW, Van Hove RA, MacLean KN, Greene NDE, Van Hove JLK. A Nonketotic Hyperglycinemia Mouse Shows Wide-Ranging Biochemical Consequences of Elevated Glycine, Reduced Folate One-Carbon Charging, and Serine Deficiency. J Inherit Metab Dis. 2026 Jan; 49(1):e70137.
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Li H, Zhang J, Bulwith L, Niswander L. Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids. Adv Sci (Weinh). 2026 Feb; 13(8):e13609.
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Shimada H, Urschitz J, Powell TL, Jansson T, Rosario FJ. Inducible trophoblast-specific knockdown of mechanistic target of rapamycin impairs placental folate transport in mice. J Nutr Biochem. 2026 Mar; 149:110189.
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Goh YE, Duggal M, Das R, Manger MS, Jamwal M, Singh BL, Brar GK, Long JM, Westcott J, Thompson L, Arnold CD, Krebs NF, Brown KH, McDonald CM. Effects of quintuply-fortified salt on the micronutrient status of females of reproductive age in Punjab, India: a randomized, community-based trial. Am J Clin Nutr. 2025 Jul; 122(1):146-156.
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Li H, Zhang J, Niswander L. Human organoids potentially boost research into environmental factors of neural tube defects. Reprod Toxicol. 2025 08; 135:108936.
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Engelhardt D, Petersen JR, Martyr C, Kuhn-Gale H, Niswander LA. Moderate levels of folic acid benefit outcomes for cilia based neural tube defects. Dev Biol. 2025 04; 520:62-74.
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Yu SM, King E, Fribourg M, Hartzell S, Tsou L, Gee L, D'Agati VD, Thurman JM, He JC, Cravedi P. A Newly Identified Protective Role of C5a Receptor 1 in Kidney Tubules against Toxin-Induced Acute Kidney Injury. Am J Pathol. 2025 Jan; 195(1):126-142.
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Maclean KN, Jiang H, Neill PD, Chanin RR, Hurt KJ, Orlicky DJ, Bottiglieri T, Roede JR, Stabler SP. Dysregulation of hepatic one-carbon metabolism in classical homocystinuria: Implications of redox-sensitive DHFR repression and tetrahydrofolate depletion for pathogenesis and treatment. FASEB J. 2024 Jul 15; 38(13):e23795.
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Maitin-Shepard M, O'Tierney-Ginn P, Kraneveld AD, Lyall K, Fallin D, Arora M, Fasano A, Mueller NT, Wang X, Caulfield LE, Dickerson AS, Diaz Heijtz R, Tarui T, Blumberg JB, Holingue C, Schmidt RJ, Garssen J, Almendinger K, Lin PD, Mozaffarian D. Food, nutrition, and autism: from soil to fork. Am J Clin Nutr. 2024 07; 120(1):240-256.
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