 Betaine
"Betaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)
| Descriptor ID |
D001622
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| MeSH Number(s) |
D02.092.877.883.077 D02.675.276.125
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| Concept/Terms |
Betaine- Betaine
- Lycine
- Oxyneurine
- Glycine Betaine
- Betaine, Glycine
C.B.B.- C.B.B.
- Citrate de Bétaïne Beaufour
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Below are MeSH descriptors whose meaning is more general than "Betaine".
Below are MeSH descriptors whose meaning is more specific than "Betaine".
This graph shows the total number of publications written about "Betaine" by people in this website by year, and whether "Betaine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 1 | 3 | | 2010 | 3 | 1 | 4 | | 2011 | 1 | 1 | 2 | | 2012 | 2 | 2 | 4 | | 2013 | 0 | 2 | 2 | | 2016 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Betaine" by people in Profiles.
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James KL, Gertz ER, Kirschke CP, Allayee H, Huang L, Kable ME, Newman JW, Stephensen CB, Bennett BJ. Trimethylamine N-Oxide Response to a Mixed Macronutrient Tolerance Test in a Cohort of Healthy United States Adults. Int J Mol Sci. 2023 Jan 20; 24(3).
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Maclean KN, Jiang H, Phinney WN, Mclagan BM, Roede JR, Stabler SP. Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis. Mol Genet Metab. 2021 02; 132(2):128-138.
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Ebert T, Painer J, Bergman P, Qureshi AR, Giroud S, Stalder G, Kublickiene K, G?ritz F, Vetter S, Bieber C, Fr?bert O, Arnemo JM, Zedrosser A, Redtenbacher I, Shiels PG, Johnson RJ, Stenvinkel P. Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears. Sci Rep. 2020 11 23; 10(1):20323.
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Park I, Bublil EM, Glavin F, Majtan T. Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria. Nutrients. 2020 Sep 22; 12(9).
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Yadon N, Owen A, Cakora P, Bustamante A, Hall-South A, Smith N, Felder MR, Vrana PB, Shorter KR. A high methyl donor diet affects physiology and behavior in Peromyscus polionotus. Physiol Behav. 2019 10 01; 209:112615.
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Maclean KN, Jiang H, Phinney WN, Keating AK, Hurt KJ, Stabler SP. Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine ?-synthase-deficient homocystinuria. FASEB J. 2019 05; 33(5):6339-6353.
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Carmali S, Murata H, Matyjaszewski K, Russell AJ. Tailoring Site Specificity of Bioconjugation Using Step-Wise Atom-Transfer Radical Polymerization on Proteins. Biomacromolecules. 2018 10 08; 19(10):4044-4051.
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Eyring KR, Pedersen BS, Maclean KN, Stabler SP, Yang IV, Schwartz DA. Methylene-tetrahydrofolate reductase contributes to allergic airway disease. PLoS One. 2018; 13(1):e0190916.
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Blaber EA, Pecaut MJ, Jonscher KR. Spaceflight Activates Autophagy Programs and the Proteasome in Mouse Liver. Int J Mol Sci. 2017 Sep 27; 18(10).
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Checkley W, Deza MP, Klawitter J, Romero KM, Klawitter J, Pollard SL, Wise RA, Christians U, Hansel NN. Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches. Respir Med. 2016 12; 121:59-66.
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