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																		 Vitamin B 12 Deficiency
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Vitamin B 12 Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)
    
			 
				
				
					
						| Descriptor ID | D014806 |  
						| MeSH Number(s) | C18.654.521.500.133.699.923 |  
						| Concept/Terms | Vitamin B 12 DeficiencyVitamin B 12 DeficiencyVitamin B12 DeficiencyDeficiency, Vitamin B12Deficiencies, Vitamin B12Vitamin B12 DeficienciesDeficiency, Vitamin B 12
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				Below are MeSH descriptors whose meaning is more general than "Vitamin B 12 Deficiency". 
				Below are MeSH descriptors whose meaning is more specific than "Vitamin B 12 Deficiency". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Vitamin B 12 Deficiency" by people in this website by year, and whether "Vitamin B 12 Deficiency" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1995 | 2 | 1 | 3 |  | 1996 | 5 | 0 | 5 |  | 1997 | 1 | 0 | 1 |  | 1998 | 3 | 0 | 3 |  | 1999 | 1 | 0 | 1 |  | 2000 | 3 | 1 | 4 |  | 2002 | 2 | 1 | 3 |  | 2003 | 1 | 1 | 2 |  | 2004 | 2 | 1 | 3 |  | 2005 | 2 | 1 | 3 |  | 2006 | 2 | 0 | 2 |  | 2007 | 2 | 0 | 2 |  | 2009 | 1 | 1 | 2 |  | 2010 | 1 | 0 | 1 |  | 2011 | 1 | 2 | 3 |  | 2013 | 2 | 0 | 2 |  | 2014 | 2 | 0 | 2 |  | 2015 | 2 | 0 | 2 |  | 2016 | 0 | 1 | 1 |  | 2017 | 2 | 0 | 2 |  | 2019 | 1 | 0 | 1 |  | 2020 | 1 | 0 | 1 |  | 2022 | 1 | 0 | 1 |  | 2025 | 0 | 1 | 1 | 
 
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				Below are the most recent publications written about "Vitamin B 12 Deficiency" by people in Profiles. 		
					
								
								Goh YE, Duggal M, Das R, Manger MS, Jamwal M, Singh BL, Brar GK, Long JM, Westcott J, Thompson L, Arnold CD, Krebs NF, Brown KH, McDonald CM. Effects of quintuply-fortified salt on the micronutrient status of females of reproductive age in Punjab, India: a randomized, community-based trial. Am J Clin Nutr. 2025 Jul; 122(1):146-156.
								Candelario N, Klein C. Megaloblastic anemia due to severe vitamin B12 deficiency. Cleve Clin J Med. 2022 01 04; 89(1):8-9.
								Stabler SP. Alterations in Sulfur Amino Acids as Biomarkers of Disease. J Nutr. 2020 10 01; 150(Suppl 1):2532S-2537S.
								Sremba L, McCandless S, Baker P. Concerning "Diagnostic Exome Sequencing and Tailored Bioinformatics of the Parents of a Deceased Child with Cobalamin Deficiency Suggests Digenic Inheritance of the MTR and LMBRD1 Genes" by Farwell Gonzalez et al. J Inherit Metab Dis. 2020 03; 43(2):157-158.
								Green R, Allen LH, Bj?rke-Monsen AL, Brito A, Gu?ant JL, Miller JW, Molloy AM, Nexo E, Stabler S, Toh BH, Ueland PM, Yajnik C. Vitamin B12 deficiency. Nat Rev Dis Primers. 2017 Jun 29; 3:17040.
								Scalais E, Osterheld E, Weitzel C, De Meirleir L, Mataigne F, Martens G, Shaikh TH, Coughlin CR, Yu HC, Swanson M, Friederich MW, Scharer G, Helbling D, Wendt-Andrae J, Van Hove JLK. X-Linked Cobalamin Disorder (HCFC1) Mimicking Nonketotic Hyperglycinemia With Increased Both Cerebrospinal Fluid Glycine and Methylmalonic Acid. Pediatr Neurol. 2017 Jun; 71:65-69.
								McMahon B, Kamath S. Pancytopenia in a Patient With Hypothyroidism. JAMA. 2016 Apr 19; 315(15):1648-9.
								Weisfeld-Adams JD, McCourt EA, Diaz GA, Oliver SC. Ocular disease in the cobalamin C defect: a review of the literature and a suggested framework for clinical surveillance. Mol Genet Metab. 2015 Apr; 114(4):537-46.
								Kurnat-Thoma EL, Pangilinan F, Matteini AM, Wong B, Pepper GA, Stabler SP, Guralnik JM, Brody LC. Association of Transcobalamin II (TCN2) and Transcobalamin II-Receptor (TCblR) Genetic Variations With Cobalamin Deficiency Parameters in Elderly Women. Biol Res Nurs. 2015 Jul; 17(4):444-54.
								Stabler SP. Anemias due to essential nutrient deficiencies. World Rev Nutr Diet. 2015; 111:164-8. | 
																	
																		
																			
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