 Homocysteine
"Homocysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiol-containing amino acid formed by a demethylation of METHIONINE.
| Descriptor ID |
D006710
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| MeSH Number(s) |
D02.886.030.498 D12.125.166.498
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| Concept/Terms |
Homocysteine- Homocysteine
- 2-amino-4-mercaptobutyric acid
- 2 amino 4 mercaptobutyric acid
- Homocysteine, L-Isomer
- Homocysteine, L Isomer
- L-Isomer Homocysteine
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Below are MeSH descriptors whose meaning is more general than "Homocysteine".
Below are MeSH descriptors whose meaning is more specific than "Homocysteine".
This graph shows the total number of publications written about "Homocysteine" by people in this website by year, and whether "Homocysteine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 1 | 3 | | 1995 | 1 | 1 | 2 | | 1996 | 6 | 2 | 8 | | 1997 | 3 | 0 | 3 | | 1998 | 1 | 1 | 2 | | 1999 | 1 | 2 | 3 | | 2000 | 4 | 2 | 6 | | 2001 | 1 | 2 | 3 | | 2002 | 3 | 3 | 6 | | 2003 | 0 | 2 | 2 | | 2004 | 5 | 2 | 7 | | 2005 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 4 | 1 | 5 | | 2008 | 0 | 2 | 2 | | 2009 | 2 | 2 | 4 | | 2010 | 3 | 2 | 5 | | 2011 | 4 | 0 | 4 | | 2012 | 2 | 3 | 5 | | 2013 | 1 | 2 | 3 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 4 | 4 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 3 | 3 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Homocysteine" by people in Profiles.
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Kripps KA, Sremba L, Larson AA, Van Hove JLK, Nguyen H, Wright EL, Mirsky DM, Watkins D, Rosenblatt DS, Ketteridge D, Berry SA, McCandless SE, Baker PR. Methionine synthase deficiency: Variable clinical presentation and benefit of early diagnosis and treatment. J Inherit Metab Dis. 2022 03; 45(2):157-168.
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Maclean KN, Jiang H, Phinney WN, Mclagan BM, Roede JR, Stabler SP. Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis. Mol Genet Metab. 2021 02; 132(2):128-138.
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Ko?ich V, Stabler S. Lessons Learned from Inherited Metabolic Disorders of Sulfur-Containing Amino Acids Metabolism. J Nutr. 2020 10 01; 150(Suppl 1):2506S-2517S.
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Park I, Bublil EM, Glavin F, Majtan T. Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria. Nutrients. 2020 Sep 22; 12(9).
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Mehrpour O, Modi M, Mansouri B, Azadi NA, Nakhaee S, Amirabadi A, Anaei-Sarab G, Shirazi FM, Weiss ST. Comparison of Vitamin B12, Vitamin D, and Folic Acid Blood Levels in Plumbism Patients and Controls in Eastern Iran. Biol Trace Elem Res. 2021 Jan; 199(1):9-17.
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Van Hove JLK, Freehauf CL, Ficicioglu C, Pena LDM, Moreau KL, Henthorn TK, Christians U, Jiang H, Cowan TM, Young SP, Hite M, Friederich MW, Stabler SP, Spector EB, Kronquist KE, Thomas JA, Emmett P, Harrington MJ, Pyle L, Creadon-Swindell G, Wempe MF, MacLean KN. Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine ?-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial. J Inherit Metab Dis. 2019 05; 42(3):424-437.
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Keller AC, Klawitter J, Hildreth KL, Christians U, Putnam K, Kohrt WM, Reusch JEB, Moreau KL. Elevated plasma homocysteine and cysteine are associated with endothelial dysfunction across menopausal stages in healthy women. J Appl Physiol (1985). 2019 06 01; 126(6):1533-1540.
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Raffield LM, Ellis J, Olson NC, Duan Q, Li J, Durda P, Pankratz N, Keating BJ, Wassel CL, Cushman M, Wilson JG, Gross MD, Tracy RP, Rich SS, Reiner AP, Li Y, Willis MS, Lange EM, Lange LA. Genome-wide association study of homocysteine in African Americans from the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Coronary Artery Risk in Young Adults study. J Hum Genet. 2018 Mar; 63(3):327-337.
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Gim?nez-Mascarell P, Majtan T, Oyenarte I, Ere?o-Orbea J, Majtan J, Klaudiny J, Kraus JP, Mart?nez-Cruz LA. Crystal structure of cystathionine ?-synthase from honeybee Apis mellifera. J Struct Biol. 2018 04; 202(1):82-93.
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Majtan T, Krijt J, Sokolov? J, Kr?kov? M, Ralat MA, Kent J, Gregory JF, Ko?ich V, Kraus JP. Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase. Antioxid Redox Signal. 2018 02 01; 28(4):311-323.
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