 Amanitins
"Amanitins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species, blocking the production of mRNA and protein synthesis. These peptides are important in the study of transcription. Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals.
| Descriptor ID |
D000546
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| MeSH Number(s) |
D04.345.566.050 D12.644.456.050 D12.644.641.050 D23.946.587.175
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Amanitins".
Below are MeSH descriptors whose meaning is more specific than "Amanitins".
This graph shows the total number of publications written about "Amanitins" by people in this website by year, and whether "Amanitins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amanitins" by people in Profiles.
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Ghosh M, Liu G, Randall G, Bevington J, Leffak M. Transcription factor binding and induced transcription alter chromosomal c-myc replicator activity. Mol Cell Biol. 2004 Dec; 24(23):10193-207.
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Bird G, Zorio DA, Bentley DL. RNA polymerase II carboxy-terminal domain phosphorylation is required for cotranscriptional pre-mRNA splicing and 3'-end formation. Mol Cell Biol. 2004 Oct; 24(20):8963-9.
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de la Mata M, Alonso CR, Kadener S, Fededa JP, Blaustein M, Pelisch F, Cramer P, Bentley D, Kornblihtt AR. A slow RNA polymerase II affects alternative splicing in vivo. Mol Cell. 2003 Aug; 12(2):525-32.
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Woontner M, Jaehning JA. Accurate initiation of mRNA synthesis in extracts from Schizosaccharomyces pombe, Kluyveromyces lactis and Candida glabrata. Yeast. 1993 Dec; 9(12):1331-4.
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Shirazi Y, Rus HG, Macklin WB, Shin ML. Enhanced degradation of messenger RNA encoding myelin proteins by terminal complement complexes in oligodendrocytes. J Immunol. 1993 May 15; 150(10):4581-90.
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Woontner M, Jaehning JA. Accurate initiation by RNA polymerase II in a whole cell extract from Saccharomyces cerevisiae. J Biol Chem. 1990 Jun 05; 265(16):8979-82.
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Metz DH, Oxman MN, Levin MJ. Interferon inhibits the in vitro accumulation of virus specific RNA in nuclei isolated from SV40 infected cells. Biochem Biophys Res Commun. 1977 Mar 07; 75(1):172-8.
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