 Enzyme Inhibitors
"Enzyme Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
| Descriptor ID |
D004791
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| MeSH Number(s) |
D27.505.519.389
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Enzyme Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Inhibitors".
This graph shows the total number of publications written about "Enzyme Inhibitors" by people in this website by year, and whether "Enzyme Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1995 | 3 | 4 | 7 | | 1996 | 6 | 13 | 19 | | 1997 | 6 | 21 | 27 | | 1998 | 4 | 16 | 20 | | 1999 | 10 | 18 | 28 | | 2000 | 7 | 28 | 35 | | 2001 | 9 | 38 | 47 | | 2002 | 14 | 47 | 61 | | 2003 | 13 | 34 | 47 | | 2004 | 8 | 37 | 45 | | 2005 | 11 | 22 | 33 | | 2006 | 8 | 21 | 29 | | 2007 | 14 | 16 | 30 | | 2008 | 11 | 21 | 32 | | 2009 | 9 | 21 | 30 | | 2010 | 11 | 18 | 29 | | 2011 | 14 | 13 | 27 | | 2012 | 12 | 21 | 33 | | 2013 | 7 | 19 | 26 | | 2014 | 14 | 18 | 32 | | 2015 | 9 | 15 | 24 | | 2016 | 9 | 11 | 20 | | 2017 | 5 | 6 | 11 | | 2018 | 4 | 6 | 10 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Enzyme Inhibitors" by people in Profiles.
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Zukin LM, Pedler MG, Chyung K, Seiwald S, Lenhart P, Shieh B, Petrash JM. Aldose reductase inhibition enhances lens regeneration in mice. Chem Biol Interact. 2019 Jul 01; 307:58-62.
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Julien C, Tomberlin C, Roberts CM, Akram A, Stein GH, Silverman MA, Link CD. In vivo induction of membrane damage by ß-amyloid peptide oligomers. Acta Neuropathol Commun. 2018 11 29; 6(1):131.
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Billin AN, Honeycutt SE, McDougal AV, Kerr JP, Chen Z, Freudenberg JM, Rajpal DK, Luo G, Kramer HF, Geske RS, Fang F, Yao B, Clark RV, Lepore J, Cobitz A, Miller R, Nosaka K, Hinken AC, Russell AJ. HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury. Skelet Muscle. 2018 11 13; 8(1):35.
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Pryce G, Baker D. Oligoclonal bands in multiple sclerosis; Functional significance and therapeutic implications. Does the specificity matter? Mult Scler Relat Disord. 2018 Oct; 25:131-137.
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Zukin LM, Pedler MG, Groman-Lupa S, Pantcheva M, Ammar DA, Petrash JM. Aldose Reductase Inhibition Prevents Development of Posterior Capsular Opacification in an In Vivo Model of Cataract Surgery. Invest Ophthalmol Vis Sci. 2018 07 02; 59(8):3591-3598.
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Ghosh P, Maurer JM, Sagerström CG. Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish. Neural Dev. 2018 06 26; 13(1):13.
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Russo AM, Lawther AJ, Prior BM, Isbel L, Somers WG, Lesku JA, Richdale AL, Dissanayake C, Kent S, Lowry CA, Hale MW. Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice. Behav Brain Res. 2019 02 01; 359:918-926.
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DiNardo CD, Stein EM, de Botton S, Roboz GJ, Altman JK, Mims AS, Swords R, Collins RH, Mannis GN, Pollyea DA, Donnellan W, Fathi AT, Pigneux A, Erba HP, Prince GT, Stein AS, Uy GL, Foran JM, Traer E, Stuart RK, Arellano ML, Slack JL, Sekeres MA, Willekens C, Choe S, Wang H, Zhang V, Yen KE, Kapsalis SM, Yang H, Dai D, Fan B, Goldwasser M, Liu H, Agresta S, Wu B, Attar EC, Tallman MS, Stone RM, Kantarjian HM. Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML. N Engl J Med. 2018 Jun 21; 378(25):2386-2398.
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Kalita D, Holm DG, LaBarbera DV, Petrash JM, Jayanty SS. Inhibition of a-glucosidase, a-amylase, and aldose reductase by potato polyphenolic compounds. PLoS One. 2018; 13(1):e0191025.
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Soderquist CR, Ewalt MD, Czuchlewski DR, Geyer JT, Rogers HJ, Hsi ED, Wang SA, Bueso-Ramos CE, Orazi A, Arber DA, Hexner EO, Babushok DV, Bagg A. Myeloproliferative neoplasms with concurrent BCR-ABL1 translocation and JAK2 V617F mutation: a multi-institutional study from the bone marrow pathology group. Mod Pathol. 2018 05; 31(5):690-704.
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