Antimetabolites
"Antimetabolites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033)
Descriptor ID |
D000963
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MeSH Number(s) |
D27.505.519.186 D27.888.569.042
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Antimetabolites".
Below are MeSH descriptors whose meaning is more specific than "Antimetabolites".
This graph shows the total number of publications written about "Antimetabolites" by people in this website by year, and whether "Antimetabolites" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 1 | 2 | 2001 | 0 | 1 | 1 | 2004 | 0 | 2 | 2 | 2005 | 0 | 2 | 2 | 2006 | 0 | 1 | 1 | 2009 | 2 | 2 | 4 | 2010 | 1 | 1 | 2 | 2011 | 1 | 1 | 2 | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antimetabolites" by people in Profiles.
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Van Matre ET, Satyanarayana G, Page 2nd RL, Levi ME, Lindenfeld J, Mueller SW. Pharmacokinetic Drug-Drug Interactions Between Immunosuppressant and Anti-Infective Agents: Antimetabolites and Corticosteroids. Ann Transplant. 2018 01 23; 23:66-74.
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Raghu G, Martinez FJ, Brown KK, Costabel U, Cottin V, Wells AU, Lancaster L, Gibson KF, Haddad T, Agarwal P, Mack M, Dasgupta B, Nnane IP, Flavin SK, Barnathan ES. CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab. Eur Respir J. 2015 Dec; 46(6):1740-50.
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Seibold LK, Sherwood MB, Kahook MY. Wound modulation after filtration surgery. Surv Ophthalmol. 2012 Nov; 57(6):530-50.
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Cai Y, Knight WE, Guo S, Li JD, Knight PA, Yan C. Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration. J Pharmacol Exp Ther. 2012 Nov; 343(2):479-88.
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Sobral LM, Aseredo F, Agostini M, Bufalino A, Pereira MC, Graner E, Coletta RD. Molecular events associated with ciclosporin A-induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts. J Periodontal Res. 2012 Apr; 47(2):149-58.
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Sottnik JL, Lori JC, Rose BJ, Thamm DH. Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo. Clin Exp Metastasis. 2011 Dec; 28(8):865-75.
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Hovind P, Rossing P, Johnson RJ, Parving HH. Serum uric acid as a new player in the development of diabetic nephropathy. J Ren Nutr. 2011 Jan; 21(1):124-7.
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Nguyen HM, Barlow LA. Differential expression of a BMP4 reporter allele in anterior fungiform versus posterior circumvallate taste buds of mice. BMC Neurosci. 2010 Oct 13; 11:129.
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Dunkin D, Kerkar N, Arnon R, Suchy F, Miloh T. Allopurinol salvage therapy in pediatric overlap autoimmune hepatitis-primary sclerosing cholangitis with 6-MMP toxicity. J Pediatr Gastroenterol Nutr. 2010 Oct; 51(4):524-6.
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Reinholz MM, Zinnen SP, Dueck AC, Dingli D, Reinholz GG, Jonart LA, Kitzmann KA, Bruzek AK, Negron V, Abdalla AK, Arendt BK, Croatt AJ, Sanchez-Perez L, Sebesta DP, L?nnberg H, Yoneda T, Nath KA, Jelinek DF, Russell SJ, Ingle JN, Spelsberg TC, Dixon HB, Karpeisky A, Lingle WL. A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites. Bone. 2010 Jul; 47(1):12-22.
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