Multienzyme Complexes
"Multienzyme Complexes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systems of enzymes which function sequentially by catalyzing consecutive reactions linked by common metabolic intermediates. They may involve simply a transfer of water molecules or hydrogen atoms and may be associated with large supramolecular structures such as MITOCHONDRIA or RIBOSOMES.
Descriptor ID |
D009097
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MeSH Number(s) |
D05.500.562 D08.811.600
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Multienzyme Complexes".
Below are MeSH descriptors whose meaning is more specific than "Multienzyme Complexes".
This graph shows the total number of publications written about "Multienzyme Complexes" by people in this website by year, and whether "Multienzyme Complexes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1993 | 0 | 1 | 1 | 1996 | 0 | 2 | 2 | 1999 | 1 | 0 | 1 | 2000 | 4 | 3 | 7 | 2001 | 1 | 1 | 2 | 2002 | 0 | 2 | 2 | 2003 | 5 | 2 | 7 | 2004 | 2 | 7 | 9 | 2005 | 1 | 1 | 2 | 2006 | 0 | 3 | 3 | 2007 | 2 | 1 | 3 | 2008 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2012 | 2 | 0 | 2 | 2013 | 1 | 0 | 1 | 2014 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2017 | 3 | 0 | 3 |
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Below are the most recent publications written about "Multienzyme Complexes" by people in Profiles.
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Liu S, Li X, Zhang L, Jiang J, Hill RC, Cui Y, Hansen KC, Zhou ZH, Zhao R. Structure of the yeast spliceosomal postcatalytic P complex. Science. 2017 12 08; 358(6368):1278-1283.
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Salinas G, Gao W, Wang Y, Bonilla M, Yu L, Novikov A, Virginio VG, Ferreira HB, Vieites M, Gladyshev VN, Gambino D, Dai S. The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I). Antioxid Redox Signal. 2017 Dec 20; 27(18):1491-1504.
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Wortmann SB, Chen MA, Colombo R, Pontoglio A, Alhaddad B, Botto LD, Yuzyuk T, Coughlin CR, Descartes M, Grunewald S, Maranda B, Mills PB, Pitt J, Potente C, Rodenburg R, Kluijtmans LA, Sampath S, Pai EF, Wevers RA, Tiller GE. Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences. J Inherit Metab Dis. 2017 05; 40(3):423-431.
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Thompson JA, Nadeau OW, Carlson GM. A model for activation of the hexadecameric phosphorylase kinase complex deduced from zero-length oxidative crosslinking. Protein Sci. 2015 Dec; 24(12):1956-63.
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Tomaras AP, McPherson CJ, Kuhn M, Carifa A, Mullins L, George D, Desbonnet C, Eidem TM, Montgomery JI, Brown MF, Reilly U, Miller AA, O'Donnell JP. LpxC inhibitors as new antibacterial agents and tools for studying regulation of lipid A biosynthesis in Gram-negative pathogens. mBio. 2014 Sep 30; 5(5):e01551-14.
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Brown MJ, Russo BC, O'Dee DM, Schmitt DM, Nau GJ. The contribution of the glycine cleavage system to the pathogenesis of Francisella tularensis. Microbes Infect. 2014 Apr; 16(4):300-9.
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Taylor WA, Mejia EM, Mitchell RW, Choy PC, Sparagna GC, Hatch GM. Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation. PLoS One. 2012; 7(11):e48628.
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Beaudin AE, Perry CA, Stabler SP, Allen RH, Stover PJ. Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. Am J Clin Nutr. 2012 Apr; 95(4):882-91.
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Griffith M, Mwenifumbo JC, Cheung PY, Paul JE, Pugh TJ, Tang MJ, Chittaranjan S, Morin RD, Asano JK, Ally AA, Miao L, Lee A, Chan SY, Taylor G, Severson T, Hou YC, Griffith OL, Cheng GS, Novik K, Moore R, Luk M, Owen D, Brown CJ, Morin GB, Gill S, Tai IT, Marra MA. Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer. Pharmacogenomics J. 2013 Apr; 13(2):148-58.
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Bomble YJ, Beckham GT, Matthews JF, Nimlos MR, Himmel ME, Crowley MF. Modeling the self-assembly of the cellulosome enzyme complex. J Biol Chem. 2011 Feb 18; 286(7):5614-23.
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