Effect of benzyl alcohol on recombinant human interleukin-1 receptor antagonist structure and hydrogen-deuterium exchange.

Alford JR, Fowler AC, Wuttke DS, Kerwin BA, Latypov RF, Carpenter JF, Randolph TW. Effect of benzyl alcohol on recombinant human interleukin-1 receptor antagonist structure and hydrogen-deuterium exchange. J Pharm Sci. 2011 Oct; 100(10):4215-24.

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subject areas

Benzyl Alcohol
Binding Sites
Chemistry, Pharmaceutical
Deuterium Exchange Measurement
Humans
Interleukin 1 Receptor Antagonist Protein
Magnetic Resonance Spectroscopy
Models, Molecular
Preservatives, Pharmaceutical
Protein Aggregates
Protein Binding
Protein Conformation
Recombinant Proteins
Structure-Activity Relationship
Technology, Pharmaceutical
Temperature

authors with profiles

Deborah S Wuttke
Theodore W Randolph