 Preservatives, Pharmaceutical
"Preservatives, Pharmaceutical" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances added to pharmaceutical preparations to protect them from chemical change or microbial action. They include ANTI-BACTERIAL AGENTS and antioxidants.
| Descriptor ID |
D011310
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| MeSH Number(s) |
D26.650.702 D27.720.744.771
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| Concept/Terms |
Preservatives, Pharmaceutical- Preservatives, Pharmaceutical
- Pharmaceutical Preservative
- Preservative, Pharmaceutical
- Pharmaceutic Aids (Preservatives)
- Preservatives, Pharmaceutic
- Pharmaceutic Preservative
- Preservative, Pharmaceutic
- Pharmaceutical Preservatives
- Pharmaceutic Preservatives
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Below are MeSH descriptors whose meaning is more general than "Preservatives, Pharmaceutical".
Below are MeSH descriptors whose meaning is more specific than "Preservatives, Pharmaceutical".
This graph shows the total number of publications written about "Preservatives, Pharmaceutical" by people in this website by year, and whether "Preservatives, Pharmaceutical" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 7 | 1 | 8 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Preservatives, Pharmaceutical" by people in Profiles.
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Reeder MJ, Zhang D, Aravamuthan SR, Warshaw EM, DeKoven JG, Silverberg JI, Adler BL, Atwater AR, Taylor JS, Houle MC, Belsito DV, Yu J, Botto N, Mowad CM, Dunnick CA, DeLeo VA, Pratt MD. More than just methylisothiazolinone: Retrospective analysis of patients with isothiazolinone allergy in North America, 2017-2020. J Am Acad Dermatol. 2024 02; 90(2):319-327.
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Orth LE, Kelly BJ, Lagasse CA, Collins SW, Ryan MF. Safety and effectiveness of albuterol solutions with and without benzalkonium chloride when administered by continuous nebulization. Am J Health Syst Pharm. 2018 Nov 15; 75(22):1791-1797.
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Bis RL, Mallela KM. Antimicrobial preservatives induce aggregation of interferon alpha-2a: the order in which preservatives induce protein aggregation is independent of the protein. Int J Pharm. 2014 Sep 10; 472(1-2):356-61.
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Seibold LK, Kahook MY. The diurnal and nocturnal effect of travoprost with sofZia on intraocular pressure and ocular perfusion pressure. Am J Ophthalmol. 2014 Jan; 157(1):44-49.e1.
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Hutchings RL, Singh SM, Cabello-Villegas J, Mallela KM. Effect of antimicrobial preservatives on partial protein unfolding and aggregation. J Pharm Sci. 2013 Feb; 102(2):365-76.
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Seibold LK, Ammar DA, Kahook MY. Acute effects of glaucoma medications and benzalkonium chloride on pre-adipocyte proliferation and adipocyte cytotoxicity in vitro. Curr Eye Res. 2013 Jan; 38(1):70-4.
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Kahook MY, Fechtner RD, Katz LJ, Noecker RJ, Ammar DA. A comparison of active ingredients and preservatives between brand name and generic topical glaucoma medications using liquid chromatography-tandem mass spectrometry. Curr Eye Res. 2012 Feb; 37(2):101-8.
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Rolando M, Crider JY, Kahook MY. Ophthalmic preservatives: focus on polyquaternium-1. Expert Opin Drug Deliv. 2011 Nov; 8(11):1425-38.
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Ammar DA, Kahook MY. Effects of benzalkonium chloride- or polyquad-preserved fixed combination glaucoma medications on human trabecular meshwork cells. Mol Vis. 2011; 17:1806-13.
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Ammar DA, Kahook MY. Effects of glaucoma medications and preservatives on cultured human trabecular meshwork and non-pigmented ciliary epithelial cell lines. Br J Ophthalmol. 2011 Oct; 95(10):1466-9.
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