Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPAR?-UCP2-AMPK axis.
Boutoual R, Meseguer S, Villarroya M, Mart?n-Hern?ndez E, Errami M, Mart?n MA, Casado M, Armengod ME. Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPAR?-UCP2-AMPK axis. Sci Rep. 2018 01 18; 8(1):1163.