 Uncoupling Protein 2
"Uncoupling Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial uncoupling protein that is expressed in many tissues and exhibits the greatest expression in SKELETAL MUSCLE. It regulates mitochondrial ATP production and the generation of REACTIVE OXYGEN SPECIES.
| Descriptor ID |
D000071246
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| MeSH Number(s) |
D12.776.157.530.937.598.750 D12.776.543.585.475.688.750 D12.776.543.585.937.696.750 D12.776.575.750.688.750
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| Concept/Terms |
Uncoupling Protein 2- Uncoupling Protein 2
- Mitochondrial Uncoupling Protein 2
- SLC25A8 Protein
- UCP2 Protein
- Uncoupling Protein-2
- Solute Carrier Family 25 Member 8
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Below are MeSH descriptors whose meaning is more general than "Uncoupling Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Uncoupling Protein 2".
This graph shows the total number of publications written about "Uncoupling Protein 2" by people in this website by year, and whether "Uncoupling Protein 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Uncoupling Protein 2" by people in Profiles.
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Rangarajan S, Locy ML, Chanda D, Kurundkar A, Kurundkar D, Larson-Casey JL, Londono P, Bagchi RA, Deskin B, Elajaili H, Nozik ES, Deshane JS, Zmijewski JW, Eickelberg O, Thannickal VJ. Mitochondrial uncoupling protein-2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age-associated lung fibrosis. Aging Cell. 2022 09; 21(9):e13674.
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Raghavan S, Kundumani-Sridharan V, Kumar S, White CW, Das KC. Thioredoxin Prevents Loss of UCP2 in Hyperoxia via MKK4-p38 MAPK-PGC1a Signaling and Limits Oxygen Toxicity. Am J Respir Cell Mol Biol. 2022 03; 66(3):323-336.
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Singh PK, Gari M, Choudhury S, Shukla A, Gangwar N, Garg SK. Oleic Acid Prevents Isoprenaline-Induced Cardiac Injury: Effects on Cellular Oxidative Stress, Inflammation and Histopathological Alterations. Cardiovasc Toxicol. 2020 02; 20(1):28-48.
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Boutoual R, Meseguer S, Villarroya M, Mart?n-Hern?ndez E, Errami M, Mart?n MA, Casado M, Armengod ME. Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPAR?-UCP2-AMPK axis. Sci Rep. 2018 01 18; 8(1):1163.
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Roshon MJ, Kline JA, Thornton LR, Watts JA. Cardiac UCP2 expression and myocardial oxidative metabolism during acute septic shock in the rat. Shock. 2003 Jun; 19(6):570-6.
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Kimm SY, Glynn NW, Aston CE, Damcott CM, Poehlman ET, Daniels SR, Ferrell RE. Racial differences in the relation between uncoupling protein genes and resting energy expenditure. Am J Clin Nutr. 2002 Apr; 75(4):714-9.
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