 Dihydroxyphenylalanine
"Dihydroxyphenylalanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
| Descriptor ID |
D004295
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| MeSH Number(s) |
D02.092.311.200 D12.125.072.050.685.400 D12.125.072.050.875.130
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| Concept/Terms |
Dihydroxyphenylalanine- Dihydroxyphenylalanine
- beta-Hydroxytyrosine
- beta Hydroxytyrosine
- 3-Hydroxy-DL-tyrosine
- 3 Hydroxy DL tyrosine
- 3,4-Dihydroxyphenylalanine
- 3,4 Dihydroxyphenylalanine
- Dopa
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Below are MeSH descriptors whose meaning is more general than "Dihydroxyphenylalanine".
Below are MeSH descriptors whose meaning is more specific than "Dihydroxyphenylalanine".
This graph shows the total number of publications written about "Dihydroxyphenylalanine" by people in this website by year, and whether "Dihydroxyphenylalanine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dihydroxyphenylalanine" by people in Profiles.
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Eisenberg DP, Yankowitz L, Ianni AM, Rubinstein DY, Kohn PD, Hegarty CE, Gregory MD, Apud JA, Berman KF. Presynaptic Dopamine Synthesis Capacity in Schizophrenia and Striatal Blood Flow Change During Antipsychotic Treatment and Medication-Free Conditions. Neuropsychopharmacology. 2017 Oct; 42(11):2232-2241.
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Porter EB, Polaski JT, Morck MM, Batey RT. Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors. Nat Chem Biol. 2017 03; 13(3):295-301.
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Vasiliadou R, Nasr Esfahani MM, Brown NJ, Welham KJ. A Disposable Microfluidic Device with a Screen Printed Electrode for Mimicking Phase II Metabolism. Sensors (Basel). 2016 Sep 02; 16(9).
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Choi JY, Augagneur Y, Mamoun CB, Voelker DR. Identification of gene encoding Plasmodium knowlesi phosphatidylserine decarboxylase by genetic complementation in yeast and characterization of in vitro maturation of encoded enzyme. J Biol Chem. 2012 Jan 02; 287(1):222-232.
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Ma Y, Tang C, Chaly T, Greene P, Breeze R, Fahn S, Freed C, Dhawan V, Eidelberg D. Dopamine cell implantation in Parkinson's disease: long-term clinical and (18)F-FDOPA PET outcomes. J Nucl Med. 2010 Jan; 51(1):7-15.
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Zafar KS, Siegel D, Ross D. A potential role for cyclized quinones derived from dopamine, DOPA, and 3,4-dihydroxyphenylacetic acid in proteasomal inhibition. Mol Pharmacol. 2006 Sep; 70(3):1079-86.
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Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, Kao R, Dillon S, Winfield H, Culver S, Trojanowski JQ, Eidelberg D, Fahn S. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med. 2001 Mar 08; 344(10):710-9.
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Esler MD, Thompson JM, Kaye DM, Turner AG, Jennings GL, Cox HS, Lambert GW, Seals DR. Effects of aging on the responsiveness of the human cardiac sympathetic nerves to stressors. Circulation. 1995 Jan 15; 91(2):351-8.
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Esler MD, Turner AG, Kaye DM, Thompson JM, Kingwell BA, Morris M, Lambert GW, Jennings GL, Cox HS, Seals DR. Aging effects on human sympathetic neuronal function. Am J Physiol. 1995 Jan; 268(1 Pt 2):R278-85.
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Rothstein JD, Tabakoff B. Effects of the convulsant methionine sulfoximine on striatal dopamine metabolism. J Neurochem. 1982 Aug; 39(2):452-7.
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