 Methyldopa
"Methyldopa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent.
| Descriptor ID |
D008750
|
| MeSH Number(s) |
D02.092.311.200.538 D12.125.072.050.685.400.600 D12.125.072.050.875.130.600
|
| Concept/Terms |
Methyldopa- Methyldopa
- alpha-Methyl-L-Dopa
- alpha Methyl L Dopa
- alpha-Methyldopa
- alpha Methyldopa
- Alphamethyldopa
|
Below are MeSH descriptors whose meaning is more general than "Methyldopa".
Below are MeSH descriptors whose meaning is more specific than "Methyldopa".
This graph shows the total number of publications written about "Methyldopa" by people in this website by year, and whether "Methyldopa" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Methyldopa" by people in Profiles.
-
Ostrov DA, Gottlieb PA, Michels AW. Rationally designed small molecules to prevent type 1 diabetes. Curr Opin Endocrinol Diabetes Obes. 2019 04; 26(2):90-95.
-
Ostrov DA, Alkanani A, McDaniel KA, Case S, Baschal EE, Pyle L, Ellis S, P?llinger B, Seidl KJ, Shah VN, Garg SK, Atkinson MA, Gottlieb PA, Michels AW. Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. J Clin Invest. 2018 05 01; 128(5):1888-1902.
-
Freed CR, Wang CH, U'Prichard DC. Changes in brain alpha-adrenergic receptors after alpha-methyldopa administration to spontaneously hypertensive rats. Hypertension. 1984 Sep-Oct; 6(5 Pt 2):II34-9.
-
Freed CR, Asmus PA. Brain tissue and plasma assay of L-DOPA and alpha-methyldopa metabolites by high performance liquid chromatography with electrochemical detection. J Neurochem. 1979 Jan; 32(1):163-8.
-
Freed CR, Weinkam RJ, Melmon KL, Castagnoli N. Chemical lonization mass spectrometric measurement of alpha-methyldopa and s-dopa metabolites in rat brain regions. Anal Biochem. 1977 Apr; 78(2):319-32.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|