 Cimetidine
"Cimetidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
| Descriptor ID |
D002927
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| MeSH Number(s) |
D02.078.370.200 D03.383.129.308.130
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| Concept/Terms |
Cimetidine- Cimetidine
- N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine
SK&F-92334- SK&F-92334
- SK&F 92334
- SK&F92334
- SKF-92334
- SKF 92334
- SKF92334
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Below are MeSH descriptors whose meaning is more general than "Cimetidine".
Below are MeSH descriptors whose meaning is more specific than "Cimetidine".
This graph shows the total number of publications written about "Cimetidine" by people in this website by year, and whether "Cimetidine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cimetidine" by people in Profiles.
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Mills D, Gordon EJ, Casano A, Lahti SM, Nguyen T, Preston A, Tondre J, Wu K, Yanase T, Chan H, Chia D, Esfandiari M, Himmel T, Love SM. The physiology of the normal human breast: an exploratory study. J Physiol Biochem. 2011 Dec; 67(4):621-7.
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Baican A, Norris DA, Birlea SA. Recalcitrant Grysbovski's keratoacanthomas with good response to cimetidine. Am J Med. 2010 Apr; 123(4):e9-10.
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H?rbelt M, Wotzlaw C, Sutton TA, Molitoris BA, Philipp T, Kribben A, Fandrey J, Pietruck F. Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy. Kidney Int. 2007 Aug; 72(4):422-9.
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Coogan PF, Zhang Y, Palmer JR, Strom BL, Rosenberg L. Cimetidine and other histamine2-receptor antagonist use in relation to risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 2005 Apr; 14(4):1012-5.
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Ruscin JM, Page RL, Valuck RJ. Vitamin B(12) deficiency associated with histamine(2)-receptor antagonists and a proton-pump inhibitor. Ann Pharmacother. 2002 May; 36(5):812-6.
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Burkhart KK, Janco N, Kulig KW, Rumack BH. Cimetidine as adjunctive treatment for acetaminophen overdose. Hum Exp Toxicol. 1995 Mar; 14(3):299-304.
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Vannier E, Dinarello CA. Histamine enhances interleukin (IL)-1-induced IL-6 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. J Biol Chem. 1994 Apr 01; 269(13):9952-6.
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Occena RO, Taylor SF, Robinson CC, Sokol RJ. Association of cytomegalovirus with M?n?trier's disease in childhood: report of two new cases with a review of literature. J Pediatr Gastroenterol Nutr. 1993 Aug; 17(2):217-24.
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Vannier E, Miller LC, Dinarello CA. Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors. J Exp Med. 1991 Jul 01; 174(1):281-4.
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Mughal TI, Robinson WA, Thomas MR, Spiegel R. Role of recombinant interferon alpha 2 and cimetidine in patients with advanced malignant melanoma. J Cancer Res Clin Oncol. 1988; 114(1):108-9.
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