Pinacidil
"Pinacidil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
| Descriptor ID |
D020110
|
| MeSH Number(s) |
D02.078.370.729
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pinacidil".
Below are MeSH descriptors whose meaning is more specific than "Pinacidil".
This graph shows the total number of publications written about "Pinacidil" by people in this website by year, and whether "Pinacidil" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pinacidil" by people in Profiles.
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Tang DG, Pavot DR, Mouria MM, Holwitt DM, Cohen NM. Warm ischemia lung protection with pinacidil: an ATP regulated potassium channel opener. Ann Thorac Surg. 2003 Aug; 76(2):385-9; discussion 389-90.
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Kowaltowski AJ, Seetharaman S, Paucek P, Garlid KD. Bioenergetic consequences of opening the ATP-sensitive K(+) channel of heart mitochondria. Am J Physiol Heart Circ Physiol. 2001 Feb; 280(2):H649-57.