Clotrimazole
"Clotrimazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.
| Descriptor ID |
D003022
|
| MeSH Number(s) |
D03.383.129.308.175
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Clotrimazole".
Below are MeSH descriptors whose meaning is more specific than "Clotrimazole".
This graph shows the total number of publications written about "Clotrimazole" by people in this website by year, and whether "Clotrimazole" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clotrimazole" by people in Profiles.
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Nakayama S, Vest R, Traystman RJ, Herson PS. Sexually dimorphic response of TRPM2 inhibition following cardiac arrest-induced global cerebral ischemia in mice. J Mol Neurosci. 2013 Sep; 51(1):92-8.
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Jia J, Verma S, Nakayama S, Quillinan N, Grafe MR, Hurn PD, Herson PS. Sex differences in neuroprotection provided by inhibition of TRPM2 channels following experimental stroke. J Cereb Blood Flow Metab. 2011 Nov; 31(11):2160-8.
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Forward ZA, Legendre AM, Khalsa HD. Use of intermittent bladder infusion with clotrimazole for treatment of candiduria in a dog. J Am Vet Med Assoc. 2002 May 15; 220(10):1496-8, 1474-5.