 Biguanides
"Biguanides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
| Descriptor ID |
D001645
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| MeSH Number(s) |
D02.078.370.141
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Biguanides".
Below are MeSH descriptors whose meaning is more specific than "Biguanides".
This graph shows the total number of publications written about "Biguanides" by people in this website by year, and whether "Biguanides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 2 | 2 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Biguanides" by people in Profiles.
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Mehrpour O, Saeedi F, Nakhaee S, Tavakkoli Khomeini F, Hadianfar A, Amirabadizadeh A, Hoyte C. Comparison of decision tree with common machine learning models for prediction of biguanide and sulfonylurea poisoning in the United States: an analysis of the National Poison Data System. BMC Med Inform Decis Mak. 2023 04 06; 23(1):60.
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Mehrpour O, Nakhaee S, Saeedi F, Valizade B, Lotfi E, Nawaz MH. Utility of artificial intelligence to identify antihyperglycemic agents poisoning in the USA: introducing a practical web application using National Poison Data System (NPDS). Environ Sci Pollut Res Int. 2023 Apr; 30(20):57801-57810.
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Vallejo A, Wallis M, McMillan D. Use of low-frequency contact ultrasonic debridement with and without polyhexamethylene biguanide in hard-to-heal leg ulcers: an RCT. J Wound Care. 2022 Aug 02; 31(8):670-681.
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Josey KP, Yang F, Ghosh D, Raghavan S. A calibration approach to transportability and data-fusion with observational data. Stat Med. 2022 10 15; 41(23):4511-4531.
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Vallejo A, Wallis M, McMillan D, Horton E. Use of low-frequency contact ultrasonic debridement with and without polyhexamethylene biguanide in hard-to-heal leg ulcers: an RCT protocol. J Wound Care. 2021 May 02; 30(5):372-379.
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Wang GS, Hoyte C. Review of Biguanide (Metformin) Toxicity. J Intensive Care Med. 2019 Nov-Dec; 34(11-12):863-876.
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de Vries A, Paton JF, Lightman SL, Lowry CA. Characterisation of c-Fos expression in the central nervous system of mice following right atrial injections of the 5-HT3 receptor agonist phenylbiguanide. Auton Neurosci. 2005 Dec 30; 123(1-2):62-75.
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Mochizuki S, Watanabe T, Miyake A, Saito M, Furuichi K. Cloning, expression, and characterization of ferret 5-HT(3) receptor subunit. Eur J Pharmacol. 2000 Jul 07; 399(2-3):97-106.
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Mochizuki S, Miyake A, Furuichi K. Identification of a domain affecting agonist potency of meta-chlorophenylbiguanide in 5-HT3 receptors. Eur J Pharmacol. 1999 Mar 12; 369(1):125-32.
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Watkins LR, McGorry M, Schwartz B, Sisk D, Wiertelak EP, Maier SF. Reversal of spinal cord non-opiate analgesia by conditioned anti-analgesia in the rat. Pain. 1997 Jul; 71(3):237-47.
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