Guanethidine
"Guanethidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
| Descriptor ID |
D006145
|
| MeSH Number(s) |
D02.078.370.460
|
| Concept/Terms |
Guanethidine- Guanethidine
- Oktadin
- ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
- Octadine
|
Below are MeSH descriptors whose meaning is more general than "Guanethidine".
Below are MeSH descriptors whose meaning is more specific than "Guanethidine".
This graph shows the total number of publications written about "Guanethidine" by people in this website by year, and whether "Guanethidine" was a major or minor topic of these publications.
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Below are the most recent publications written about "Guanethidine" by people in Profiles.
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Drummond PD. Depletion of noradrenaline inhibits electrically-evoked pain in the skin of the human forearm. Eur J Pain. 2008 Feb; 12(2):196-202.
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Drummond PD. Immersion of the hand in ice water releases adrenergic vasoconstrictor tone in the ipsilateral temple. Auton Neurosci. 2006 Jul 30; 128(1-2):70-5.
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Altiere RJ, Diamond L, Thompson DC. Omega-conotoxin-sensitive calcium channels modulate autonomic neurotransmission in guinea pig airways. J Pharmacol Exp Ther. 1992 Jan; 260(1):98-103.