 Mitochondrial Dynamics
"Mitochondrial Dynamics" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The continuous remodeling of MITOCHONDRIA shape by fission and fusion in response to physiological conditions.
| Descriptor ID |
D063154
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| MeSH Number(s) |
G04.599.750
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| Concept/Terms |
Mitochondrial Dynamics- Mitochondrial Dynamics
- Dynamic, Mitochondrial
- Dynamics, Mitochondrial
- Mitochondrial Dynamic
- Mitochondrial Fission and Fusion
- Mitochondrial Fusion and Fission
Mitochondrial Fission- Mitochondrial Fission
- Fission, Mitochondrial
- Fissions, Mitochondrial
- Mitochondrial Fissions
Mitochondrial Fusion- Mitochondrial Fusion
- Fusion, Mitochondrial
- Fusions, Mitochondrial
- Mitochondrial Fusions
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Below are MeSH descriptors whose meaning is more general than "Mitochondrial Dynamics".
Below are MeSH descriptors whose meaning is more specific than "Mitochondrial Dynamics".
This graph shows the total number of publications written about "Mitochondrial Dynamics" by people in this website by year, and whether "Mitochondrial Dynamics" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 3 | 0 | 3 | | 2014 | 2 | 0 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 2 | 2 | | 2019 | 2 | 2 | 4 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 1 | 3 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 3 | 0 | 3 | | 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Mitochondrial Dynamics" by people in Profiles.
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Willett BAS, Thompson SB, Chen V, Dareshouri A, Jackson CL, Brunetti T, D'Alessandro A, Klarquist J, Nemkov T, Kedl RM. Mitochondrial protein OPA1 is required for the expansion of effector CD8 T cells. Cell Rep. 2025 May 27; 44(5):115610.
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Sun X, Yegambaram M, Lu Q, Garcia Flores AE, Pokharel MD, Soto J, Aggarwal S, Wang T, Fineman JR, Black SM. Mitochondrial fission produces a Warburg effect via the oxidative inhibition of prolyl hydroxylase domain-2. Redox Biol. 2025 Apr; 81:103529.
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Pokharel MD, Feng A, Liang Y, Ma W, Aggarwal S, Unwalla H, Black SM, Wang T. Drp1-associated genes implicated in sepsis survival. Front Immunol. 2024; 15:1516145.
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Fogo GM, Raghunayakula S, Emaus KJ, Torres Torres FJ, Wider JM, Sanderson TH. Mitochondrial membrane potential and oxidative stress interact to regulate Oma1-dependent processing of Opa1 and mitochondrial dynamics. FASEB J. 2024 Sep 30; 38(18):e70066.
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Pokharel MD, Fu P, Garcia-Flores A, Yegambaram M, Lu Q, Sun X, Unwalla H, Aggarwal S, Fineman JR, Wang T, Black SM. Inflammatory lung injury is associated with endothelial cell mitochondrial fission and requires the nitration of RhoA and cytoskeletal remodeling. Free Radic Biol Med. 2024 Aug 20; 221:125-135.
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Pokharel MD, Garcia-Flores A, Marciano D, Franco MC, Fineman JR, Aggarwal S, Wang T, Black SM. Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics. Redox Biol. 2024 04; 70:103049.
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von der Malsburg A, Sapp GM, Zuccaro KE, von Appen A, Moss FR, Kalia R, Bennett JA, Abriata LA, Dal Peraro M, van der Laan M, Frost A, Aydin H. Structural mechanism of mitochondrial membrane remodelling by human OPA1. Nature. 2023 Aug; 620(7976):1101-1108.
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Hua F, Zhu H, Yu W, Zheng Q, Zhang L, Liang W, Lin Y, Xiao F, Yi P, Xiong Y, Dong Y, Li H, Fang L, Liu H, Ying J, Wang X. ?-arrestin1 regulates astrocytic reactivity via Drp1-dependent mitochondrial fission: implications in postoperative delirium. J Neuroinflammation. 2023 May 11; 20(1):113.
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Sessions DT, Kim KB, Kashatus JA, Churchill N, Park KS, Mayo MW, Sesaki H, Kashatus DF. Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma. Cell Rep. 2022 12 13; 41(11):111818.
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Ghosh JC, Perego M, Agarwal E, Bertolini I, Wang Y, Goldman AR, Tang HY, Kossenkov AV, Landis CJ, Languino LR, Plow EF, Morotti A, Ottobrini L, Locatelli M, Speicher DW, Caino MC, Cassel J, Salvino JM, Robert ME, Vaira V, Altieri DC. Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).
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