 Dosage Compensation, Genetic
"Dosage Compensation, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female.
| Descriptor ID |
D004303
|
| MeSH Number(s) |
G05.308.203.249
|
| Concept/Terms |
Dosage Compensation, Genetic- Dosage Compensation, Genetic
- Compensation, Genetic Dosage
- Genetic Dosage Compensation
- Genetic Dosage Compensations
- Gene Dosage Compensation
- Compensation, Gene Dosage
- Dosage Compensation, Gene
- Gene Dosage Compensations
- Dosage Compensation (Genetics)
- Compensation, Dosage (Genetics)
X-Chromosome Hypertranscription- X-Chromosome Hypertranscription
- X Chromosome Hypertranscription
- Hypertranscription, X-Chromosome
- Hypertranscription, X Chromosome
|
Below are MeSH descriptors whose meaning is more general than "Dosage Compensation, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Dosage Compensation, Genetic".
This graph shows the total number of publications written about "Dosage Compensation, Genetic" by people in this website by year, and whether "Dosage Compensation, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Dosage Compensation, Genetic" by people in Profiles.
-
Hunter S, Hendrix J, Freeman J, Dowell RD, Allen MA. Transcription dosage compensation does not occur in Down syndrome. BMC Biol. 2023 11 10; 21(1):228.
-
Carter AC, Xu J, Nakamoto MY, Wei Y, Zarnegar BJ, Shi Q, Broughton JP, Ransom RC, Salhotra A, Nagaraja SD, Li R, Dou DR, Yost KE, Cho SW, Mistry A, Longaker MT, Khavari PA, Batey RT, Wuttke DS, Chang HY. Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation. Elife. 2020 05 07; 9.
-
Schield DR, Card DC, Hales NR, Perry BW, Pasquesi GM, Blackmon H, Adams RH, Corbin AB, Smith CF, Ramesh B, Demuth JP, Betr?n E, Tollis M, Meik JM, Mackessy SP, Castoe TA. The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes. Genome Res. 2019 04; 29(4):590-601.
-
Chuong EB, Feschotte C. Evolution. Transposons up the dosage. Science. 2013 Nov 15; 342(6160):812-3.
-
Baker PR, Tsai AC, Springer M, Swisshelm K, March J, Brown K, Bellus G. Male with mosaicism for supernumerary ring X chromosome: analysis of phenotype and characterization of genotype using array comparative genome hybridization. J Craniofac Surg. 2010 Sep; 21(5):1369-75.
-
Janssen WJ, Dhaliwal G, Collard HR, Saint S. Clinical problem-solving. Why "why" matters. N Engl J Med. 2004 Dec 02; 351(23):2429-34.
-
Stone LM, Tan SS, Tam PP, Finger TE. Analysis of cell lineage relationships in taste buds. J Neurosci. 2002 Jun 01; 22(11):4522-9.
-
Clayton RN, Pfeifer M, Atkinson AB, Belchetz P, Wass JA, Kyrodimou E, Vanderpump M, Simpson D, Bicknell J, Farrell WE. Different patterns of allelic loss (loss of heterozygosity) in recurrent human pituitary tumors provide evidence for multiclonal origins. Clin Cancer Res. 2000 Oct; 6(10):3973-82.
-
Disteche CM, Swisshelm K, Forbes S, Pagon RA. X-inactivation patterns in lymphocytes and skin fibroblasts of three cases of X-autosome translocations with abnormal phenotypes. Hum Genet. 1984; 66(1):71-6.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|