 Werner Syndrome
"Werner Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin changes, cataracts, subcutaneous calcification, muscular atrophy, a tendency to diabetes mellitus, aged appearance of the face, baldness, and a high incidence of neoplastic disease.
| Descriptor ID |
D014898
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| MeSH Number(s) |
C16.320.925 C18.452.284.960
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| Concept/Terms |
Werner Syndrome- Werner Syndrome
- Syndrome, Werner
- Adult Progeria
- Werner's Syndrome
- Syndrome, Werner's
- Werners Syndrome
- Syndrome, Werners
- Adult Premature Aging Syndrome
- Progeria, Adult
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Below are MeSH descriptors whose meaning is more general than "Werner Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Werner Syndrome".
This graph shows the total number of publications written about "Werner Syndrome" by people in this website by year, and whether "Werner Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Werner Syndrome" by people in Profiles.
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Zhang W, Li J, Suzuki K, Qu J, Wang P, Zhou J, Liu X, Ren R, Xu X, Ocampo A, Yuan T, Yang J, Li Y, Shi L, Guan D, Pan H, Duan S, Ding Z, Li M, Yi F, Bai R, Wang Y, Chen C, Yang F, Li X, Wang Z, Aizawa E, Goebl A, Soligalla RD, Reddy P, Esteban CR, Tang F, Liu GH, Belmonte JC. Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging. Science. 2015 Jun 05; 348(6239):1160-3.
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Hsu JJ, Kamath-Loeb AS, Glick E, Wallden B, Swisshelm K, Rubin BP, Loeb LA. Werner syndrome gene variants in human sarcomas. Mol Carcinog. 2010 Feb; 49(2):166-74.
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Grandori C, Robinson KL, Galloway DA, Swisshelm K. Functional link between Myc and the Werner gene in tumorigenesis. Cell Cycle. 2004 Jan; 3(1):22-5.
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Grandori C, Wu KJ, Fernandez P, Ngouenet C, Grim J, Clurman BE, Moser MJ, Oshima J, Russell DW, Swisshelm K, Frank S, Amati B, Dalla-Favera R, Monnat RJ. Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev. 2003 Jul 01; 17(13):1569-74.
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Verneris M, McDougall IR, Becton D, Link MP. Thyroid carcinoma after successful treatment of osteosarcoma: a report of three patients. J Pediatr Hematol Oncol. 2001 Jun-Jul; 23(5):312-5.
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