 Pregabalin
"Pregabalin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.
| Descriptor ID |
D000069583
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| MeSH Number(s) |
D02.241.081.114.500.350.500 D12.125.190.350.450
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| Concept/Terms |
Pregabalin- Pregabalin
- (S)-3-(aminomethyl)-5-methylhexanoic acid
- 3-isobutyl GABA
- 3 isobutyl GABA
- GABA, 3-isobutyl
- 3-(aminomethyl)-5-methylhexanoic acid
- (R-)-3-isobutyl GABA
- (S+)-3-isobutyl GABA
CI 1008- CI 1008
- 1008, CI
- CI-1008
- CI1008
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Below are MeSH descriptors whose meaning is more general than "Pregabalin".
Below are MeSH descriptors whose meaning is more specific than "Pregabalin".
This graph shows the total number of publications written about "Pregabalin" by people in this website by year, and whether "Pregabalin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pregabalin" by people in Profiles.
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Winslow BT, Vandal C, Dang L. Fibromyalgia: Diagnosis and Management. Am Fam Physician. 2023 02; 107(2):137-144.
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Ibiloye EA, Barner JC, Lawson KA, Rascati KL, Evoy KE, Peckham AM. Prevalence of and Factors Associated with Gabapentinoid Use and Misuse Among Texas Medicaid Recipients. Clin Drug Investig. 2021 Mar; 41(3):245-253.
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Barohn RJ, Gajewski B, Pasnoor M, Brown A, Herbelin LL, Kimminau KS, Mudaranthakam DP, Jawdat O, Dimachkie MM, Iyadurai S, Stino A, Kissel J, Pascuzzi R, Brannagan T, Wicklund M, Ahmed A, Walk D, Smith G, Quan D, Heitzman D, Tobon A, Ladha S, Wolfe G, Pulley M, Hayat G, Li Y, Thaisetthawatkul P, Lewis R, Biliciler S, Sharma K, Salajegheh K, Trivedi J, Mallonee W, Burns T, Jacoby M, Bril V, Vu T, Ramchandren S, Bazant M, Austin S, Karam C, Hussain Y, Kutz C, Twydell P, Scelsa S, Kushlaf H, Wymer J, Hehir M, Kolb N, Ralph J, Barboi A, Verma N, Ahmed M, Memon A, Saperstein D, Lou JS, Swenson A, Cash T. Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized Trial. JAMA Neurol. 2021 01 01; 78(1):68-76.
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Coutens B, Mouledous L, Stella M, Rampon C, Lapeyre-Mestre M, Roussin A, Guiard BP, Jouanjus E. Lack of correlation between the activity of the mesolimbic dopaminergic system and the rewarding properties of pregabalin in mouse. Psychopharmacology (Berl). 2019 Jul; 236(7):2069-2082.
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Wei LA, Davies BW, Hink EM, Durairaj VD. Perioperative pregabalin for attenuation of postoperative pain after eyelid surgery. Ophthalmic Plast Reconstr Surg. 2015 Mar-Apr; 31(2):132-5.
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Kapil V, Green JL, Le Lait MC, Wood DM, Dargan PI. Misuse of the ?-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK. Br J Clin Pharmacol. 2014 Jul; 78(1):190-1.
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Simpson DM, Rice AS, Emir B, Landen J, Semel D, Chew ML, Sporn J. A randomized, double-blind, placebo-controlled trial and open-label extension study to evaluate the efficacy and safety of pregabalin in the treatment of neuropathic pain associated with human immunodeficiency virus neuropathy. Pain. 2014 Oct; 155(10):1943-54.
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Mullen KR, Schwark W, Divers TJ. Pharmacokinetics of single-dose intragastric and intravenous pregabalin administration in clinically normal horses. Am J Vet Res. 2013 Jul; 74(7):1043-8.
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Simpson DM, Schifitto G, Clifford DB, Murphy TK, Durso-De Cruz E, Glue P, Whalen E, Emir B, Scott GN, Freeman R. Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial. Neurology. 2010 Feb 02; 74(5):413-20.
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Page RL, Cantu M, Lindenfeld J, Hergott LJ, Lowes BD. Possible heart failure exacerbation associated with pregabalin: case discussion and literature review. J Cardiovasc Med (Hagerstown). 2008 Sep; 9(9):922-5.
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