Son of Sevenless Proteins
"Son of Sevenless Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS that are genetically related to the Son of Sevenless gene from DROSOPHILA. Sevenless refers to genetic mutations in DROSOPHILA that cause loss of the R7 photoreceptor which is required to see UV light.
Descriptor ID |
D020664
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MeSH Number(s) |
D12.644.360.325.300.700.700 D12.776.476.325.300.700.700
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Son of Sevenless Proteins".
Below are MeSH descriptors whose meaning is more specific than "Son of Sevenless Proteins".
This graph shows the total number of publications written about "Son of Sevenless Proteins" by people in this website by year, and whether "Son of Sevenless Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 2 | 2 | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Son of Sevenless Proteins" by people in Profiles.
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Chie L, Chen JM, Friedman FK, Chung DL, Amar S, Michl J, Yamaizumi Z, Brandt-Rauf PW, Pincus MR. Inhibition of oncogenic and activated wild-type ras-p21 protein-induced oocyte maturation by peptides from the guanine-nucleotide exchange protein, SOS, identified from molecular dynamics calculations. Selective inhibition of oncogenic ras-p21. J Protein Chem. 1999 Nov; 18(8):875-9.
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Kimura A, Ohmichi M, Takeda T, Kurachi H, Ikegami H, Koike K, Masuhara K, Hayakawa J, Kanzaki T, Kobayashi M, Akabane M, Inoue M, Miyake A, Murata Y. Mitogen-activated protein kinase cascade is involved in endothelin-1-induced rat puerperal uterine contraction. Endocrinology. 1999 Feb; 140(2):722-31.
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Schubert C, Carel K, DePaolo D, Leitner W, Draznin B. Interactions of protein kinase C with insulin signaling. Influence on GAP and Sos activities. J Biol Chem. 1996 Jun 28; 271(26):15311-4.
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Sasaoka T, Langlois WJ, Bai F, Rose DW, Leitner JW, Decker SJ, Saltiel A, Gill GN, Kobayashi M, Draznin B, Olefsky JM. Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites. J Biol Chem. 1996 Apr 05; 271(14):8338-44.
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