 Receptor-Like Protein Tyrosine Phosphatases, Class 4
"Receptor-Like Protein Tyrosine Phosphatases, Class 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of receptor-like protein tryosine phosphatases that contain short highly glycosylated extracellular domains and two active cytosolic protein tyrosine phosphatase domains.
| Descriptor ID |
D054630
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| MeSH Number(s) |
D08.811.277.352.650.775.400.400 D12.644.360.587.400 D12.776.476.592.400
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| Concept/Terms |
Receptor-Like Protein Tyrosine Phosphatases, Class 4- Receptor-Like Protein Tyrosine Phosphatases, Class 4
- Receptor Like Protein Tyrosine Phosphatases, Class 4
- Receptor-Like Protein Tyrosine Phosphatases, Class IV
- Receptor Like Protein Tyrosine Phosphatases, Class IV
Protein Tyrosine Phosphatase, Receptor Type E- Protein Tyrosine Phosphatase, Receptor Type E
- R-PTP-epsilon
- R PTP epsilon
- Protein-Tyrosine Phosphatase epsilon
- Phosphatase epsilon, Protein-Tyrosine
- Protein Tyrosine Phosphatase epsilon
Protein Tyrosine Phosphatase, Receptor Type A- Protein Tyrosine Phosphatase, Receptor Type A
- R-PTP-alpha Phosphatase
- Phosphatase, R-PTP-alpha
- R PTP alpha Phosphatase
- Protein-Tyrosine Phosphatase alpha
- Phosphatase alpha, Protein-Tyrosine
- Protein Tyrosine Phosphatase alpha
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Below are MeSH descriptors whose meaning is more general than "Receptor-Like Protein Tyrosine Phosphatases, Class 4".
Below are MeSH descriptors whose meaning is more specific than "Receptor-Like Protein Tyrosine Phosphatases, Class 4".
This graph shows the total number of publications written about "Receptor-Like Protein Tyrosine Phosphatases, Class 4" by people in this website by year, and whether "Receptor-Like Protein Tyrosine Phosphatases, Class 4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor-Like Protein Tyrosine Phosphatases, Class 4" by people in Profiles.
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Sendo S, Kiosses WB, Yang S, Wu DJ, Lee DWK, Liu L, Aschner Y, Vela AJ, Downey GP, Santelli E, Bottini N. Clustering of phosphatase RPTPa promotes Src signaling and the arthritogenic action of synovial fibroblasts. Sci Signal. 2023 07 04; 16(792):eabn8668.
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Aschner Y, Correll KA, Beke KM, Foster DG, Roybal HM, Nelson MR, Meador CL, Strand M, Anderson KC, Moore CM, Reynolds PR, Kopf KW, Burnham EL, Downey GP. PTPa promotes fibroproliferative responses after acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2022 07 01; 323(1):L69-L83.
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Aschner Y, Nelson M, Brenner M, Roybal H, Beke K, Meador C, Foster D, Correll KA, Reynolds PR, Anderson K, Redente EF, Matsuda J, Riches DWH, Groshong SD, Pozzi A, Sap J, Wang Q, Rajshankar D, McCulloch CAG, Zemans RL, Downey GP. Protein tyrosine phosphatase-a amplifies transforming growth factor-?-dependent profibrotic signaling in lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L294-L311.
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Wang Q, Wang Y, Downey GP, Plotnikov S, McCulloch CA. A ternary complex comprising FAK, PTPa and IP3 receptor 1 functionally engages focal adhesions and the endoplasmic reticulum to mediate IL-1-induced Ca2+ signalling in fibroblasts. Biochem J. 2016 Feb 15; 473(4):397-410.
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Wang Q, Wang Y, Fritz D, Rajshankar D, Downey GP, McCulloch CA. Interactions of the protein-tyrosine phosphatase-a with the focal adhesion targeting domain of focal adhesion kinase are involved in interleukin-1 signaling in fibroblasts. J Biol Chem. 2014 Jun 27; 289(26):18427-41.
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Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP. Protein tyrosine phosphatase a mediates profibrotic signaling in lung fibroblasts through TGF-? responsiveness. Am J Pathol. 2014 May; 184(5):1489-502.
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Rajshankar D, Sima C, Wang Q, Goldberg SR, Kazembe M, Wang Y, Glogauer M, Downey GP, McCulloch CA. Role of PTPa in the destruction of periodontal connective tissues. PLoS One. 2013; 8(8):e70659.
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Wang Q, Rajshankar D, Laschinger C, Talior-Volodarsky I, Wang Y, Downey GP, McCulloch CA. Importance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and interleukin-1-induced matrix metalloproteinase-3 expression. J Biol Chem. 2010 Jul 16; 285(29):22308-17.
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Wang Q, Rajshankar D, Branch DR, Siminovitch KA, Herrera Abreu MT, Downey GP, McCulloch CA. Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling. J Biol Chem. 2009 Jul 31; 284(31):20763-72.
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Herrera Abreu MT, Penton PC, Kwok V, Vachon E, Shalloway D, Vidali L, Lee W, McCulloch CA, Downey GP. Tyrosine phosphatase PTPalpha regulates focal adhesion remodeling through Rac1 activation. Am J Physiol Cell Physiol. 2008 Apr; 294(4):C931-44.
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