 Phagosomes
"Phagosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-bound cytoplasmic vesicles formed by invagination of phagocytized material. They fuse with lysosomes to form phagolysosomes in which the hydrolytic enzymes of the lysosome digest the phagocytized material.
| Descriptor ID |
D010588
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| MeSH Number(s) |
A11.284.430.214.190.875.190.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phagosomes".
Below are MeSH descriptors whose meaning is more specific than "Phagosomes".
This graph shows the total number of publications written about "Phagosomes" by people in this website by year, and whether "Phagosomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2001 | 2 | 0 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2008 | 0 | 2 | 2 | | 2009 | 0 | 2 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 2 | 4 | | 2014 | 3 | 1 | 4 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 | | 2019 | 0 | 1 | 1 | | 2020 | 2 | 0 | 2 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phagosomes" by people in Profiles.
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Villanueva JA, Crooks AL, Nagy TA, Quintana JLJ, Dalebroux ZD, Detweiler CS. Salmonella enterica Infections Are Disrupted by Two Small Molecules That Accumulate within Phagosomes and Differentially Damage Bacterial Inner Membranes. mBio. 2022 10 26; 13(5):e0179022.
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Pajuelo D, Tak U, Zhang L, Danilchanka O, Tischler AD, Niederweis M. Toxin secretion and trafficking by Mycobacterium tuberculosis. Nat Commun. 2021 11 15; 12(1):6592.
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Walpole GFW, Plumb JD, Chung D, Tang B, Boulay B, Osborne DG, Piotrowski JT, Catz SD, Billadeau DD, Grinstein S, Jaumouill? V. Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation. Cell Rep. 2020 06 02; 31(9):107721.
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Fitzsimmons LF, Liu L, Kant S, Kim JS, Till JK, Jones-Carson J, Porwollik S, McClelland M, Vazquez-Torres A. SpoT Induces Intracellular Salmonella Virulence Programs in the Phagosome. mBio. 2020 02 25; 11(1).
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Bai X, Bai A, Honda JR, Eichstaedt C, Musheyev A, Feng Z, Huitt G, Harbeck R, Kosmider B, Sandhaus RA, Chan ED. Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria. Front Immunol. 2019; 10:1417.
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Ledvina HE, Kelly KA, Eshraghi A, Plemel RL, Peterson SB, Lee B, Steele S, Adler M, Kawula TH, Merz AJ, Skerrett SJ, Celli J, Mougous JD. A Phosphatidylinositol 3-Kinase Effector Alters Phagosomal Maturation to Promote Intracellular Growth of Francisella. Cell Host Microbe. 2018 08 08; 24(2):285-295.e8.
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Mitchell G, Cheng MI, Chen C, Nguyen BN, Whiteley AT, Kianian S, Cox JS, Green DR, McDonald KL, Portnoy DA. Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):E210-E217.
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Dimasuay KG, Gong L, Rosario F, McBryde E, Spelman T, Glazier J, Rogerson SJ, Beeson JG, Jansson T, Devenish RJ, Boeuf P. Impaired placental autophagy in placental malaria. PLoS One. 2017; 12(11):e0187291.
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Kugadas A, Lamont EA, Bannantine JP, Shoyama FM, Brenner E, Janagama HK, Sreevatsan S. A Mycobacterium avium subsp. paratuberculosis Predicted Serine Protease Is Associated with Acid Stress and Intraphagosomal Survival. Front Cell Infect Microbiol. 2016; 6:85.
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DiNardo AR, Mace EM, Lesteberg K, Cirillo JD, Mandalakas AM, Graviss EA, Orange JS, Makedonas G. Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4+ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation. J Infect Dis. 2016 08 01; 214(3):479-88.
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