 Gene Products, rev
"Gene Products, rev" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. rev is short for regulator of virion.
| Descriptor ID |
D015694
|
| MeSH Number(s) |
D12.776.157.725.076 D12.776.664.962.186 D12.776.964.925.984.385
|
| Concept/Terms |
Gene Products, rev- Gene Products, rev
- rev Gene Products
- rev Protein
- Gene Product, rev
- rev Gene Product
|
Below are MeSH descriptors whose meaning is more general than "Gene Products, rev".
Below are MeSH descriptors whose meaning is more specific than "Gene Products, rev".
This graph shows the total number of publications written about "Gene Products, rev" by people in this website by year, and whether "Gene Products, rev" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2004 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Gene Products, rev" by people in Profiles.
-
Llano M, Vanegas M, Fregoso O, Saenz D, Chung S, Peretz M, Poeschla EM. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J Virol. 2004 Sep; 78(17):9524-37.
-
Nguyen KL, llano M, Akari H, Miyagi E, Poeschla EM, Strebel K, Bour S. Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression. Virology. 2004 Feb 20; 319(2):163-75.
-
Bai J, Banda N, Lee NS, Rossi J, Akkina R. RNA-based anti-HIV-1 gene therapeutic constructs in SCID-hu mouse model. Mol Ther. 2002 Dec; 6(6):770-82.
-
Gold L. RNA as the catalyst for drug screening. Nat Biotechnol. 2002 Jul; 20(7):671-2.
-
Jensen KB, Atkinson BL, Willis MC, Koch TH, Gold L. Using in vitro selection to direct the covalent attachment of human immunodeficiency virus type 1 Rev protein to high-affinity RNA ligands. Proc Natl Acad Sci U S A. 1995 Dec 19; 92(26):12220-4.
-
Harrison GS, Maxwell F, Long CJ, Rosen CA, Glode LM, Maxwell IH. Activation of a diphtheria toxin A gene by expression of human immunodeficiency virus-1 Tat and Rev proteins in transfected cells. Hum Gene Ther. 1991; 2(1):53-60.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|