Sodium-Potassium-Exchanging ATPase
"Sodium-Potassium-Exchanging ATPase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wall. Sodium and potassium ions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients.
| Descriptor ID |
D000254
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| MeSH Number(s) |
D08.811.277.040.025.314.750 D12.776.157.530.450.162.780 D12.776.157.530.450.250.880 D12.776.157.530.813.750 D12.776.543.585.450.162.800 D12.776.543.585.450.250.890 D12.776.543.585.813.750
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| Concept/Terms |
Sodium-Potassium-Exchanging ATPase- Sodium-Potassium-Exchanging ATPase
- ATPase, Sodium-Potassium-Exchanging
- Sodium Potassium Exchanging ATPase
- Sodium, Potassium Adenosinetriphosphatase
- Adenosinetriphosphatase Sodium, Potassium
- ATPase, Sodium, Potassium
- Sodium, Potassium ATPase
- ATPase Sodium, Potassium
- Potassium Pump
- Pump, Potassium
- Sodium, Potassium Adenosine Triphosphatase
- Sodium-Potassium Pump
- Pump, Sodium-Potassium
- Sodium Potassium Pump
- Na(+) K(+)-Transporting ATPase
- Na(+)-K(+)-Transporting ATPase
- Na(+)-K(+)-Exchanging ATPase
- Adenosine Triphosphatase, Sodium, Potassium
- Adenosinetriphosphatase, Sodium, Potassium
- Sodium Pump
- Pump, Sodium
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Below are MeSH descriptors whose meaning is more general than "Sodium-Potassium-Exchanging ATPase".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Potassium-Exchanging ATPase".
This graph shows the total number of publications written about "Sodium-Potassium-Exchanging ATPase" by people in this website by year, and whether "Sodium-Potassium-Exchanging ATPase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1997 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2002 | 2 | 0 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2008 | 1 | 2 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 1 | 3 | | 2012 | 2 | 1 | 3 | | 2013 | 3 | 1 | 4 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 3 | 0 | 3 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Potassium-Exchanging ATPase" by people in Profiles.
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Moya-Mendez ME, Bidzimou MT, Muralidharan P, Zhang Z, Ezekian JE, Perelli RM, Parker LE, Prange L, Boggs A, Kim JJ, Howard TS, Word TA, Wehrens XHT, Reyes Valenzuela G, Caraballo R, Garone G, Vigevano F, Weckhuysen S, Millevert C, Troncoso M, Matamala M, Balestrini S, Sisodiya SM, Poole J, Zucca C, Panagiotakaki E, Papadopoulou MT, Tchaicha S, Zawadzka M, Mazurkiewicz-Beldzinska M, Fons C, Anticona J, De Grandis E, Cordani R, Pisciotta L, Groppa S, Paryjas S, Ragona F, Mangia E, Granata T, Megvinov A, Pavlicek M, Ess K, Simmons CQ, George AL, Vavassori R, Mikati MA, Landstrom AP. ATP1A3 Variants, Variably Penetrant Short QT Intervals, and Lethal Ventricular Arrhythmias. JAMA Pediatr. 2025 May 01; 179(5):529-539.
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Springer CS, Baker EM, Li X, Moloney B, Pike MM, Wilson GJ, Anderson VC, Sammi MK, Garzotto MG, Kopp RP, Coakley FV, Rooney WD, Maki JH. Metabolic activity diffusion imaging (MADI): II. Noninvasive, high-resolution human brain mapping of sodium pump flux and cell metrics. NMR Biomed. 2023 01; 36(1):e4782.
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Morotti S, Ni H, Peters CH, Rickert C, Asgari-Targhi A, Sato D, Glukhov AV, Proenza C, Grandi E. Intracellular Na+ Modulates Pacemaking Activity in Murine Sinoatrial Node Myocytes: An In Silico Analysis. Int J Mol Sci. 2021 May 26; 22(11).
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Snow JP, Westlake G, Klofas LK, Jeon S, Armstrong LC, Swoboda KJ, George AL, Ess KC. Neuronal modeling of alternating hemiplegia of childhood reveals transcriptional compensation and replicates a trigger-induced phenotype. Neurobiol Dis. 2020 07; 141:104881.
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Arystarkhova E, Haq IU, Luebbert T, Mochel F, Saunders-Pullman R, Bressman SB, Feschenko P, Salazar C, Cook JF, Demarest S, Brashear A, Ozelius LJ, Sweadner KJ. Factors in the disease severity of ATP1A3 mutations: Impairment, misfolding, and allele competition. Neurobiol Dis. 2019 12; 132:104577.
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Racine ML, Crecelius AR, Luckasen GJ, Larson DG, Dinenno FA. Inhibition of Na+ /K+ -ATPase and KIR channels abolishes hypoxic hyperaemia in resting but not contracting skeletal muscle of humans. J Physiol. 2018 08; 596(15):3371-3389.
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Simmons CQ, Thompson CH, Cawthon BE, Westlake G, Swoboda KJ, Kiskinis E, Ess KC, George AL. Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood. Neurobiol Dis. 2018 07; 115:29-38.
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Iwasaki M, Minder P, CaƬ Y, Kuhn JH, Yates JR, Torbett BE, de la Torre JC. Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses. PLoS Pathog. 2018 02; 14(2):e1006892.
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Hearon CM, Richards JC, Racine ML, Luckasen GJ, Larson DG, Joyner MJ, Dinenno FA. Sympatholytic effect of intravascular ATP is independent of nitric oxide, prostaglandins, Na+ /K+ -ATPase and KIR channels in humans. J Physiol. 2017 08 01; 595(15):5175-5190.
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Gritz SM, Larson C, Radcliffe RA. Atp1a2 contributes modestly to alcohol-related behaviors. Alcohol. 2016 11; 56:29-37.
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