 H(+)-K(+)-Exchanging ATPase
"H(+)-K(+)-Exchanging ATPase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme isolated from the GASTRIC MUCOSA that catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions across the cell wall. This enzyme was formerly listed as EC 3.6.1.36.
| Descriptor ID |
D017506
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| MeSH Number(s) |
D08.811.277.040.025.314.625 D12.776.157.530.450.250.875.500.625 D12.776.157.530.813.625 D12.776.543.585.450.250.875.500.625 D12.776.543.585.813.625
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| Concept/Terms |
H(+)-K(+)-Exchanging ATPase- H(+)-K(+)-Exchanging ATPase
- Potassium Hydrogen ATPase
- ATPase, Potassium Hydrogen
- ATPase, Hydrogen, Potassium
- Hydrogen, Potassium ATPase
- ATPase Hydrogen, Potassium
- Adenosinetriphosphatase, Hydrogen, Potassium
- Hydrogen-Potassium-Exchanging ATPase
- ATPase, Hydrogen-Potassium-Exchanging
- Hydrogen Potassium Exchanging ATPase
- H(+)-K(+)-Transporting ATPase
- Adenosine Triphosphatase, Hydrogen, Potassium
- Hydrogen, Potassium, Adenosine Triphosphatase
- Gastric H(+) K(+) ATPase
- Hydrogen, Potassium, Adenosinetriphosphatase
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Below are MeSH descriptors whose meaning is more general than "H(+)-K(+)-Exchanging ATPase".
Below are MeSH descriptors whose meaning is more specific than "H(+)-K(+)-Exchanging ATPase".
This graph shows the total number of publications written about "H(+)-K(+)-Exchanging ATPase" by people in this website by year, and whether "H(+)-K(+)-Exchanging ATPase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "H(+)-K(+)-Exchanging ATPase" by people in Profiles.
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Lahner E, Marzinotto I, Lampasona V, Dottori L, Bazzigaluppi E, Brigatti C, Secchi M, Piemonti L, Conti L, Pilozzi E, Davidson HW, Wenzlau JM, Annibale B. Autoantibodies Toward ATP4A and ATP4B Subunits of Gastric Proton Pump H+,K+-ATPase Are Reliable Serological Pre-endoscopic Markers of Corpus Atrophic Gastritis. Clin Transl Gastroenterol. 2020 10; 11(10):e00240.
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Lahner E, Marzinotto I, Brigatti C, Davidson H, Wenzlau J, Piemonti L, Annibale B, Lampasona V. Measurement of Autoantibodies to Gastric H+,K+-ATPase (ATP4A/B) Using a Luciferase Immunoprecipitation System (LIPS). Methods Mol Biol. 2019; 1901:113-131.
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Kozhakhmetova A, Wyatt RC, Caygill C, Williams C, Long AE, Chandler K, Aitken RJ, Wenzlau JM, Davidson HW, Gillespie KM, Williams AJK. A quarter of patients with type 1 diabetes have co-existing non-islet autoimmunity: the findings of a UK population-based family study. Clin Exp Immunol. 2018 06; 192(3):251-258.
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Chobot A, Rusak E, Wenzlau J, Davidson H, Adamczyk P, Krzywicka A, Mazur B, Polanska J, Rewers M. ATP4A autoimmunity in pediatric patients with type 1 diabetes and its relationship to blood count, iron metabolism, and vitamin B12. Pediatr Diabetes. 2018 02; 19(1):80-84.
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Wenzlau JM, Fain PR, Gardner TJ, Frisch LM, Annibale B, Hutton JC. ATPase4A Autoreactivity and Its Association With Autoimmune Phenotypes in the Type 1 Diabetes Genetics Consortium Study. Diabetes Care. 2015 Oct; 38 Suppl 2:S29-36.
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Chobot A, Wenzlau J, Bak-Drabik K, Kwiecien J, Polanska J, Rewers M. ATP4A autoimmunity and Helicobacter pylori infection in children with type 1 diabetes. Clin Exp Immunol. 2014 Sep; 177(3):598-602.
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Wenzlau JM, Gardner TJ, Frisch LM, Davidson HW, Hutton JC. Development of a novel autoantibody assay for autoimmune gastritis in type 1 diabetic individuals. Diabetes Metab Res Rev. 2011 Nov; 27(8):887-90.
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Johansson M, Jansson T, Pestov NB, Powell TL. Non-gastric H+/K+ ATPase is present in the microvillous membrane of the human placental syncytiotrophoblast. Placenta. 2004 Jul; 25(6):505-11.
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