 Sodium-Hydrogen Exchangers
"Sodium-Hydrogen Exchangers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of plasma membrane exchange glycoprotein antiporters that transport sodium ions and protons across lipid bilayers. They have critical functions in intracellular pH regulation, cell volume regulation, and cellular response to many different hormones and mitogens.
| Descriptor ID |
D017923
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| MeSH Number(s) |
D12.776.157.530.450.162.775 D12.776.157.530.937.703 D12.776.543.550.190.775 D12.776.543.585.450.162.775 D12.776.543.585.937.828
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| Concept/Terms |
Sodium-Hydrogen Exchangers- Sodium-Hydrogen Exchangers
- Exchangers, Sodium-Hydrogen
- Sodium Hydrogen Exchangers
- Na(+)-H(+)-Antiporter
- Na(+)-H(+)-Exchangers
- Sodium-Proton Antiporters
- Antiporters, Sodium-Proton
- Sodium Proton Antiporters
- Solute Carrier 9 Proteins
- SLC9 Na(+)-H(+) Exchangers
- SLC9 Protein Family
- Protein Family, SLC9
- SLC9-NHE Protein Family
- Protein Family, SLC9-NHE
- SLC9 NHE Protein Family
- SLC9 Proteins
- Solute Carrier 9 Protein Family
- Sodium-Hydrogen Antiporter
- Antiporter, Sodium-Hydrogen
- Sodium Hydrogen Antiporter
- Na(+)-H(+)-Exchanger
- Sodium-Hydrogen Exchanger
- Exchanger, Sodium-Hydrogen
- Sodium Hydrogen Exchanger
- Sodium-Proton Antiporter
- Antiporter, Sodium-Proton
- Sodium Proton Antiporter
- Sodium-Hydrogen Antiporters
- Antiporters, Sodium-Hydrogen
- Sodium Hydrogen Antiporters
- Na(+)-H(+)-Antiporters
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Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchangers".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchangers".
This graph shows the total number of publications written about "Sodium-Hydrogen Exchangers" by people in this website by year, and whether "Sodium-Hydrogen Exchangers" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1998 | 1 | 2 | 3 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 |
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Below are the most recent publications written about "Sodium-Hydrogen Exchangers" by people in Profiles.
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Jeong J, Kim W, Hens J, Dann P, Schedin P, Friedman PA, Wysolmerski JJ. NHERF1 Is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland. Endocrinology. 2019 08 01; 160(8):1797-1810.
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Singh Y, Zhou Y, Zhang S, Abdelazeem KNM, Elvira B, Salker MS, Lang F. Enhanced Reactive Oxygen Species Production, Acidic Cytosolic pH and Upregulated Na+/H+ Exchanger (NHE) in Dicer Deficient CD4+ T Cells. Cell Physiol Biochem. 2017; 42(4):1377-1389.
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Abdelazeem KNM, Singh Y, Lang F, Salker MS. Negative Effect of Ellagic Acid on Cytosolic pH Regulation and Glycolytic Flux in Human Endometrial Cancer Cells. Cell Physiol Biochem. 2017; 41(6):2374-2382.
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Kremer KN, Dudakovic A, Hess AD, Smith BD, Karp JE, Kaufmann SH, Westendorf JJ, van Wijnen AJ, Hedin KE. Histone Deacetylase Inhibitors Target the Leukemic Microenvironment by Enhancing a Nherf1-Protein Phosphatase 1a-TAZ Signaling Pathway in Osteoblasts. J Biol Chem. 2015 Dec 04; 290(49):29478-92.
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Xu L, Pan L, Li J, Huang B, Feng J, Li C, Wang S, The E, Liu Y, Yuan T, Zhen L, Liang D, Liu Y, Li L, Cui Y, Jiang X, Peng L, Chen YH. Nucleoporin 35 regulates cardiomyocyte pH homeostasis by controlling Na+-H+ exchanger-1 expression. J Mol Cell Biol. 2015 Oct; 7(5):476-85.
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Giral H, Cranston D, Lanzano L, Caldas Y, Sutherland E, Rachelson J, Dobrinskikh E, Weinman EJ, Doctor RB, Gratton E, Levi M. NHE3 regulatory factor 1 (NHERF1) modulates intestinal sodium-dependent phosphate transporter (NaPi-2b) expression in apical microvilli. J Biol Chem. 2012 Oct 12; 287(42):35047-35056.
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Goldman A, Chen H, Khan MR, Roesly H, Hill KA, Shahidullah M, Mandal A, Delamere NA, Dvorak K. The Na+/H+ exchanger controls deoxycholic acid-induced apoptosis by a H+-activated, Na+-dependent ionic shift in esophageal cells. PLoS One. 2011; 6(8):e23835.
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Giral H, Lanzano L, Caldas Y, Blaine J, Verlander JW, Lei T, Gratton E, Levi M. Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters. J Biol Chem. 2011 Apr 29; 286(17):15032-42.
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Blaine J, Weinman EJ, Cunningham R. The regulation of renal phosphate transport. Adv Chronic Kidney Dis. 2011 Mar; 18(2):77-84.
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Huang X, Morse LR, Xu Y, Zahradka J, Sychrov? H, Stashenko P, Fan F, Battaglino RA. Mutational analysis of NHAoc/NHA2 in Saccharomyces cerevisiae. Biochim Biophys Acta. 2010 Dec; 1800(12):1241-7.
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