 MAP Kinase Kinase 7
"MAP Kinase Kinase 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to CYTOKINES.
| Descriptor ID |
D048688
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| MeSH Number(s) |
D08.811.913.696.620.682.700.565.700 D08.811.913.696.620.682.725.200.700 D12.644.360.440.700 D12.776.476.440.700
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| Concept/Terms |
MAP Kinase Kinase 7- MAP Kinase Kinase 7
- PRKMK7
- Mitogen-Activated Protein Kinase Kinase 7
- Mitogen Activated Protein Kinase Kinase 7
- MAPKK7 Protein Kinase
- Protein Kinase, MAPKK7
- MEK7 Protein Kinase
- Protein Kinase, MEK7
- SKK4 Protein Kinase
- Protein Kinase, SKK4
- JNK-Activating Kinase 2
- JNK Activating Kinase 2
- SEK2 Protein Kinase
- Protein Kinase, SEK2
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Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase 7".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase 7".
This graph shows the total number of publications written about "MAP Kinase Kinase 7" by people in this website by year, and whether "MAP Kinase Kinase 7" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "MAP Kinase Kinase 7" by people in Profiles.
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Gibson ES, Woolfrey KM, Li H, Hogan PG, Nemenoff RA, Heasley LE, Dell'Acqua ML. Subcellular Localization and Activity of the Mitogen-Activated Protein Kinase Kinase 7 (MKK7) ? Isoform are Regulated through Binding to the Phosphatase Calcineurin. Mol Pharmacol. 2019 01; 95(1):20-32.
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Joetham A, Ohnishi H, Okamoto M, Takeda K, Schedel M, Domenico J, Dakhama A, Gelfand EW. Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation. J Biol Chem. 2012 May 18; 287(21):17100-17108.
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Wei X, Sun W, Fan R, Hahn J, Joetham A, Li G, Webb S, Garrington T, Dakhama A, Lucas J, Johnson GL, Gelfand EW. MEF2C regulates c-Jun but not TNF-alpha gene expression in stimulated mast cells. Eur J Immunol. 2003 Oct; 33(10):2903-9.
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Chayama K, Papst PJ, Garrington TP, Pratt JC, Ishizuka T, Webb S, Ganiatsas S, Zon LI, Sun W, Johnson GL, Gelfand EW. Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4599-604.
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Wojtaszek PA, Heasley LE, Siriwardana G, Berl T. Dominant-negative c-Jun NH2-terminal kinase 2 sensitizes renal inner medullary collecting duct cells to hypertonicity-induced lethality independent of organic osmolyte transport. J Biol Chem. 1998 Jan 09; 273(2):800-4.
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