 MAP Kinase Kinase 4
"MAP Kinase Kinase 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES and the RETINOID X RECEPTORS. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to cellular stress.
| Descriptor ID |
D048670
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| MeSH Number(s) |
D08.811.913.696.620.682.700.565.400 D08.811.913.696.620.682.725.200.400 D12.644.360.440.400 D12.776.476.440.400
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| Concept/Terms |
MAP Kinase Kinase 4- MAP Kinase Kinase 4
- JN Kinase Kinase
- JNK Kinase
- Jun Amino-Terminal Kinase Kinase
- Jun Amino Terminal Kinase Kinase
- JNK-Activating Protein Kinase
- JNK Activating Protein Kinase
- Protein Kinase, JNK-Activating
- SAP Kinase-Extracellular Signal-Regulated Kinase Kinase 1
- SAP Kinase Extracellular Signal Regulated Kinase Kinase 1
- SEK1 Protein Kinase
- Protein Kinase, SEK1
- Mitogen-Activated Protein Kinase Kinase 4
- Mitogen Activated Protein Kinase Kinase 4
- MEK4 Protein Kinase
- Protein Kinase, MEK4
- JNKK1 Protein Kinase
- Kinase, JNKK1 Protein
- Protein Kinase, JNKK1
- Stress-Activated Protein Kinase Kinase 1
- Stress Activated Protein Kinase Kinase 1
- SAPK-ERK Kinase 1
- SAPK ERK Kinase 1
- SAP Kinase Kinase 1
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Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase 4".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase 4".
This graph shows the total number of publications written about "MAP Kinase Kinase 4" by people in this website by year, and whether "MAP Kinase Kinase 4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 0 | 3 | 3 | | 2005 | 0 | 3 | 3 | | 2006 | 2 | 0 | 2 | | 2007 | 0 | 1 | 1 | | 2012 | 0 | 3 | 3 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 1 | 2 |
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Below are the most recent publications written about "MAP Kinase Kinase 4" by people in Profiles.
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Raghavan S, Kundumani-Sridharan V, Kumar S, White CW, Das KC. Thioredoxin Prevents Loss of UCP2 in Hyperoxia via MKK4-p38 MAPK-PGC1a Signaling and Limits Oxygen Toxicity. Am J Respir Cell Mol Biol. 2022 03; 66(3):323-336.
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Battisti JM, Watson LA, Naung MT, Drobish AM, Voronina E, Minnick MF. Analysis of the Caenorhabditis elegans innate immune response to Coxiella burnetii. Innate Immun. 2017 02; 23(2):111-127.
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McCullough RL, Saikia P, Pollard KA, McMullen MR, Nagy LE, Roychowdhury S. Myeloid Mixed Lineage Kinase 3 Contributes to Chronic Ethanol-Induced Inflammation and Hepatocyte Injury in Mice. Gene Expr. 2016; 17(1):61-77.
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Guo F, He H, Fu ZC, Huang S, Chen T, Papasian CJ, Morse LR, Xu Y, Battaglino RA, Yang XF, Jiang Z, Xin HB, Fu M. Adipocyte-derived PAMM suppresses macrophage inflammation by inhibiting MAPK signalling. Biochem J. 2015 Dec 15; 472(3):309-18.
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Jones CL, Gearheart CM, Fosmire S, Delgado-Martin C, Evensen NA, Bride K, Waanders AJ, Pais F, Wang J, Bhatla T, Bitterman DS, de Rijk SR, Bourgeois W, Dandekar S, Park E, Burleson TM, Madhusoodhan PP, Teachey DT, Raetz EA, Hermiston ML, M?schen M, Loh ML, Hunger SP, Zhang J, Garabedian MJ, Porter CC, Carroll WL. MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia. Blood. 2015 Nov 05; 126(19):2202-12.
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Sing A, Tsatskis Y, Fabian L, Hester I, Rosenfeld R, Serricchio M, Yau N, Bietenhader M, Shanbhag R, Jurisicova A, Brill JA, McQuibban GA, McNeill H. The atypical cadherin fat directly regulates mitochondrial function and metabolic state. Cell. 2014 Sep 11; 158(6):1293-1308.
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Kim HJ, Ravichandran K, Ozkok A, Wang Q, He Z, Jani A, Ljubanovic D, Douglas IS, Edelstein CL. The water-soluble triptolide derivative PG490-88 protects against cisplatin-induced acute kidney injury. J Pharmacol Exp Ther. 2014 Jun; 349(3):518-25.
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Chang KC, Laffin B, Ponder J, Enzs?ly A, N?meth J, LaBarbera DV, Petrash JM. Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues. Chem Biol Interact. 2013 Feb 25; 202(1-3):283-7.
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Rahman SM, Janssen RC, Choudhury M, Baquero KC, Aikens RM, de la Houssaye BA, Friedman JE. CCAAT/enhancer-binding protein ? (C/EBP?) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice. J Biol Chem. 2012 Oct 05; 287(41):34349-60.
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Joetham A, Ohnishi H, Okamoto M, Takeda K, Schedel M, Domenico J, Dakhama A, Gelfand EW. Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation. J Biol Chem. 2012 May 18; 287(21):17100-17108.
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