 Sodium-Hydrogen Exchanger 3
"Sodium-Hydrogen Exchanger 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sodium-hydrogen antiporter expressed primarily by EPITHELIAL CELLS in the kidneys, it localizes to the apical membrane of the PROXIMAL KIDNEY TUBULE, where it functions in sodium and water reabsorption and possibly calcium homeostasis. It also is expressed in heart, brain, and lung tissues and is resistant to AMILORIDE inhibition.
| Descriptor ID |
D000074083
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| MeSH Number(s) |
D12.776.157.530.450.162.775.750 D12.776.157.530.937.703.750 D12.776.543.550.190.775.750 D12.776.543.585.450.162.775.750 D12.776.543.585.937.828.750
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| Concept/Terms |
Sodium-Hydrogen Exchanger 3- Sodium-Hydrogen Exchanger 3
- Sodium Hydrogen Exchanger 3
- Na(+)-H(+) Exchanger 3
- Solute Carrier Family 9 Member 3
- NHE-3 Protein
- NHE 3 Protein
- SLC9A3 Protein
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Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchanger 3".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchanger 3".
This graph shows the total number of publications written about "Sodium-Hydrogen Exchanger 3" by people in this website by year, and whether "Sodium-Hydrogen Exchanger 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Hydrogen Exchanger 3" by people in Profiles.
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Hayasaki T, Ishimoto T, Doke T, Hirayama A, Soga T, Furuhashi K, Kato N, Kosugi T, Tsuboi N, Lanaspa MA, Johnson RJ, Maruyama S, Kadomatsu K. Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase. J Nutr Biochem. 2019 09; 71:54-62.
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Hughes JL, Doughty IM, Glazier JD, Powell TL, Jansson T, D'Souza SW, Sibley CP. Activity and expression of the Na(+)/H(+) exchanger in the microvillous plasma membrane of the syncytiotrophoblast in relation to gestation and small for gestational age birth. Pediatr Res. 2000 Nov; 48(5):652-9.
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