 Phosphatidylethanolamine N-Methyltransferase
"Phosphatidylethanolamine N-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyses three sequential METHYLATION reactions for conversion of phosphatidylethanolamine to PHOSPHATIDYLCHOLINE.
| Descriptor ID |
D050918
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| MeSH Number(s) |
D08.811.913.555.500.712
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| Concept/Terms |
Phosphatidylethanolamine N-Methyltransferase- Phosphatidylethanolamine N-Methyltransferase
- N-Methyltransferase, Phosphatidylethanolamine
- Phosphatidylethanolamine N Methyltransferase
- S-Adenosylmethionine Phosphatidylethanolamine N-Methyltransferase
- N-Methyltransferase, S-Adenosylmethionine Phosphatidylethanolamine
- Phosphatidylethanolamine N-Methyltransferase, S-Adenosylmethionine
- S Adenosylmethionine Phosphatidylethanolamine N Methyltransferase
- Phosphatidylethanolamine Methyltransferase
- Methyltransferase, Phosphatidylethanolamine
- Phosphatidylethanolamine-Phosphatidylcholine N-Methyltransferase
- N-Methyltransferase, Phosphatidylethanolamine-Phosphatidylcholine
- Phosphatidylethanolamine Phosphatidylcholine N Methyltransferase
Phosphatidylethanolamine N-Methyltransferase-2- Phosphatidylethanolamine N-Methyltransferase-2
- N-Methyltransferase-2, Phosphatidylethanolamine
- Phosphatidylethanolamine N Methyltransferase 2
- Phosphatidylethanolamine-Methyltransferase II
- Phosphatidylethanolamine Methyltransferase II
- Phospholipid Methyltransferase II
- Methyltransferase II, Phospholipid
- PHET Methyltransferase II
- Methyltransferase II, PHET
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylethanolamine N-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylethanolamine N-Methyltransferase".
This graph shows the total number of publications written about "Phosphatidylethanolamine N-Methyltransferase" by people in this website by year, and whether "Phosphatidylethanolamine N-Methyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 1 | 2 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphatidylethanolamine N-Methyltransferase" by people in Profiles.
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Jacobs RL, Jiang H, Kennelly JP, Orlicky DJ, Allen RH, Stabler SP, Maclean KN. Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria. Mol Genet Metab. 2017 04; 120(4):325-336.
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Davenport C, Yan J, Taesuwan S, Shields K, West AA, Jiang X, Perry CA, Malysheva OV, Stabler SP, Allen RH, Caudill MA. Choline intakes exceeding recommendations during human lactation improve breast milk choline content by increasing PEMT pathway metabolites. J Nutr Biochem. 2015 Sep; 26(9):903-11.
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Yan J, Jiang X, West AA, Perry CA, Malysheva OV, Brenna JT, Stabler SP, Allen RH, Gregory JF, Caudill MA. Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women. Am J Clin Nutr. 2013 Dec; 98(6):1459-67.
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Riekhof WR, Wu J, Gij?n MA, Zarini S, Murphy RC, Voelker DR. Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem. 2007 Dec 21; 282(51):36853-61.
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Mudd SH, Brosnan JT, Brosnan ME, Jacobs RL, Stabler SP, Allen RH, Vance DE, Wagner C. Methyl balance and transmethylation fluxes in humans. Am J Clin Nutr. 2007 Jan; 85(1):19-25.
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Pessi G, Choi JY, Reynolds JM, Voelker DR, Mamoun CB. In vivo evidence for the specificity of Plasmodium falciparum phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway. J Biol Chem. 2005 Apr 01; 280(13):12461-6.
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Choi JY, Martin WE, Murphy RC, Voelker DR. Phosphatidylcholine and N-methylated phospholipids are nonessential in Saccharomyces cerevisiae. J Biol Chem. 2004 Oct 01; 279(40):42321-30.
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Yang EK, Blusztajn JK, Pomfret EA, Zeisel SH. Rat and human mammary tissue can synthesize choline moiety via the methylation of phosphatidylethanolamine. Biochem J. 1988 Dec 15; 256(3):821-8.
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