Uroporphyrinogen Decarboxylase
"Uroporphyrinogen Decarboxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA.
| Descriptor ID |
D014575
|
| MeSH Number(s) |
D08.811.520.224.125.900
|
| Concept/Terms |
Uroporphyrinogen Decarboxylase- Uroporphyrinogen Decarboxylase
- Decarboxylase, Uroporphyrinogen
- Uroporphyrinogen III Decarboxylase
- Decarboxylase, Uroporphyrinogen III
- Uroporphyrinogen Carboxy-Lyase
- Carboxy-Lyase, Uroporphyrinogen
- Uroporphyrinogen Carboxy Lyase
|
Below are MeSH descriptors whose meaning is more general than "Uroporphyrinogen Decarboxylase".
Below are MeSH descriptors whose meaning is more specific than "Uroporphyrinogen Decarboxylase".
This graph shows the total number of publications written about "Uroporphyrinogen Decarboxylase" by people in this website by year, and whether "Uroporphyrinogen Decarboxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Uroporphyrinogen Decarboxylase" by people in Profiles.
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Jones MA, Taneja M, Xu Y, Chung W, Stob CM, Lash TD. An effective chromatographic separation of chicken red blood cell coproporphyrinogen oxidase and uroporphyrinogen decarboxylase, two enzymes in heme biosynthesis. Bioorg Med Chem Lett. 2004 Nov 15; 14(22):5559-64.