 Myostatin
"Myostatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A growth differentiation factor that is a potent inhibitor of SKELETAL MUSCLE growth. It may play a role in the regulation of MYOGENESIS and in muscle maintenance during adulthood.
| Descriptor ID |
D055435
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| MeSH Number(s) |
D12.644.276.954.300.925 D12.776.467.942.300.925 D23.529.942.300.925
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| Concept/Terms |
Myostatin- Myostatin
- Growth Differentiation Factor 8
- GDF-8
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Below are MeSH descriptors whose meaning is more general than "Myostatin".
Below are MeSH descriptors whose meaning is more specific than "Myostatin".
This graph shows the total number of publications written about "Myostatin" by people in this website by year, and whether "Myostatin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2008 | 2 | 3 | 5 | | 2009 | 3 | 0 | 3 | | 2010 | 5 | 0 | 5 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 0 | 2 | 2 | | 2020 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myostatin" by people in Profiles.
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Denfeld QE, Purnell JQ, Lee CS, Orwoll ES, Camacho SA, Hiatt SO, Roberts Davis M, Winters-Stone K, Woodward WR, Habecker BA. Candidate biomarkers of physical frailty in heart failure: an exploratory cross-sectional study. Eur J Cardiovasc Nurs. 2023 03 01; 22(2):149-157.
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Smith RC, Cramer MS, Mitchell PJ, Lucchesi J, Ortega AM, Livingston EW, Ballard D, Zhang L, Hanson J, Barton K, Berens S, Credille KM, Bateman TA, Ferguson VL, Ma YL, Stodieck LS. Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength. PLoS One. 2020; 15(4):e0230818.
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Kumar S, Hossain J, Inge T, Balagopal PB. Changes in Myokines in Youths With Severe Obesity Following Roux-en-Y Gastric Bypass Surgery. JAMA Surg. 2019 07 01; 154(7):668-669.
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Wurtzel CN, Gumucio JP, Grekin JA, Khouri RK, Russell AJ, Bedi A, Mendias CL. Pharmacological inhibition of myostatin protects against skeletal muscle atrophy and weakness after anterior cruciate ligament tear. J Orthop Res. 2017 11; 35(11):2499-2505.
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Barreto R, Waning DL, Gao H, Liu Y, Zimmers TA, Bonetto A. Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs. Oncotarget. 2016 Jul 12; 7(28):43442-43460.
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Harper SC, Brack A, MacDonnell S, Franti M, Olwin BB, Bailey BA, Rudnicki MA, Houser SR. Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects? Circ Res. 2016 Apr 01; 118(7):1143-50; discussion 1150.
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Zou Q, Wang X, Liu Y, Ouyang Z, Long H, Wei S, Xin J, Zhao B, Lai S, Shen J, Ni Q, Yang H, Zhong H, Li L, Hu M, Zhang Q, Zhou Z, He J, Yan Q, Fan N, Zhao Y, Liu Z, Guo L, Huang J, Zhang G, Ying J, Lai L, Gao X. Generation of gene-target dogs using CRISPR/Cas9 system. J Mol Cell Biol. 2015 Dec; 7(6):580-3.
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Bonetto A, Penna F, Aversa Z, Mercantini P, Baccino FM, Costelli P, Ziparo V, Lucia S, Rossi Fanelli F, Muscaritoli M. Early changes of muscle insulin-like growth factor-1 and myostatin gene expression in gastric cancer patients. Muscle Nerve. 2013 Sep; 48(3):387-92.
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Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM. A PGC-1a isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 2012 Dec 07; 151(6):1319-31.
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Andres-Mateos E, Mejias R, Soleimani A, Lin BM, Burks TN, Marx R, Lin B, Zellars RC, Zhang Y, Huso DL, Marr TG, Leinwand LA, Merriman DK, Cohn RD. Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels. PLoS One. 2012; 7(11):e48884.
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