 Purine Nucleotides
"Purine Nucleotides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Purines attached to a RIBOSE and a phosphate that can polymerize to form DNA and RNA.
| Descriptor ID |
D011685
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| MeSH Number(s) |
D03.633.100.759.646 D13.695.667
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Purine Nucleotides".
Below are MeSH descriptors whose meaning is more specific than "Purine Nucleotides".
This graph shows the total number of publications written about "Purine Nucleotides" by people in this website by year, and whether "Purine Nucleotides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2009 | 3 | 0 | 3 | | 2013 | 2 | 0 | 2 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Purine Nucleotides" by people in Profiles.
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Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC. Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem. 2018 05 04; 293(18):6659-6671.
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Choi YJ, Chang SJ, Gibala KS, Resendiz MJE. 8-Oxo-7,8-dihydroadenine and 8-Oxo-7,8-dihydroadenosine-Chemistry, Structure, and Function in RNA and Their Presence in Natural Products and Potential Drug Derivatives. Chemistry. 2017 May 17; 23(28):6706-6716.
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Aird KM, Zhang G, Li H, Tu Z, Bitler BG, Garipov A, Wu H, Wei Z, Wagner SN, Herlyn M, Zhang R. Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence. Cell Rep. 2013 Apr 25; 3(4):1252-65.
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Stoddard CD, Widmann J, Trausch JJ, Marcano-Vel?zquez JG, Knight R, Batey RT. Nucleotides adjacent to the ligand-binding pocket are linked to activity tuning in the purine riboswitch. J Mol Biol. 2013 May 27; 425(10):1596-611.
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Patro JN, Urban M, Kuchta RD. Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides. Biochemistry. 2009 Sep 01; 48(34):8271-8.
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Trostler M, Delier A, Beckman J, Urban M, Patro JN, Spratt TE, Beese LS, Kuchta RD. Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus. Biochemistry. 2009 Jun 02; 48(21):4633-41.
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Cavanaugh NA, Urban M, Beckman J, Spratt TE, Kuchta RD. Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase. Biochemistry. 2009 Apr 21; 48(15):3554-64.
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Beckman J, Kincaid K, Hocek M, Spratt T, Engels J, Cosstick R, Kuchta RD. Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity. Biochemistry. 2007 Jan 16; 46(2):448-60.
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Ramirez-Aguilar KA, Kuchta RD. Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry. 2004 Feb 17; 43(6):1754-62.
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Draznin B, Solomons CC, Toothaker DR, Sussman KE. Energy-dependent steps in insulin-hepatocyte interaction. Endocrinology. 1981 Jan; 108(1):8-17.
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