 Allopurinol
"Allopurinol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.
| Descriptor ID |
D000493
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| MeSH Number(s) |
D03.633.100.759.160
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Allopurinol".
Below are MeSH descriptors whose meaning is more specific than "Allopurinol".
This graph shows the total number of publications written about "Allopurinol" by people in this website by year, and whether "Allopurinol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 2 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 3 | 4 | | 2007 | 0 | 1 | 1 | | 2009 | 3 | 0 | 3 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 2 | 2 | | 2014 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 | | 2019 | 2 | 1 | 3 | | 2020 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Allopurinol" by people in Profiles.
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Muench NA, Schmitt HM, Schlamp CL, Su AA, Washington K, Nickells RW. Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations. Transl Vis Sci Technol. 2024 11 04; 13(11):24.
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Worledge CS, Kostelecky RE, Zhou L, Bhagavatula G, Colgan SP, Lee JS. Allopurinol Disrupts Purine Metabolism to Increase Damage in Experimental Colitis. Cells. 2024 02 21; 13(5).
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Suarez-Pierre A, Iguidbashian J, Kirsch MJ, Cain MT, Aftab M, Reece TB, Fullerton DA, Rove JY, Cleveland JC, Hoffman JRH. Association of cardiac preservation solution with short-term outcomes after heart transplantation. J Cardiovasc Med (Hagerstown). 2024 02 01; 25(2):158-164.
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Floege J, Johnson RJ. Hyperuricemia and progression of chronic kidney disease: to treat or not to treat? Kidney Int. 2021 01; 99(1):14-16.
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Ellis BW, Traktuev DO, Merfeld-Clauss S, Can UI, Wang M, Bergeron R, Zorlutuna P, March KL. Adipose stem cell secretome markedly improves rodent heart and human induced pluripotent stem cell-derived cardiomyocyte recovery from cardioplegic transport solution exposure. Stem Cells. 2021 02; 39(2):170-182.
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Kang DH, Sanchez-Lozada LG, Johnson RJ. Allopurinol and Chronic Kidney Disease. N Engl J Med. 2020 Oct 22; 383(17):1687-1688.
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Kuwabara M, Borghi C, Johnson RJ. Febuxostat and atrial fibrillation. Eur Heart J. 2020 08 07; 41(30):2916-2917.
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Doria A, Galecki AT, Spino C, Pop-Busui R, Cherney DZ, Lingvay I, Parsa A, Rossing P, Sigal RJ, Afkarian M, Aronson R, Caramori ML, Crandall JP, de Boer IH, Elliott TG, Goldfine AB, Haw JS, Hirsch IB, Karger AB, Maahs DM, McGill JB, Molitch ME, Perkins BA, Polsky S, Pragnell M, Robiner WN, Rosas SE, Senior P, Tuttle KR, Umpierrez GE, Wallia A, Weinstock RS, Wu C, Mauer M. Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes. N Engl J Med. 2020 06 25; 382(26):2493-2503.
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García-Arroyo FE, Monroy-Sánchez F, Muñoz-Jiménez I, Gonzaga G, Andrés-Hernando A, Zazueta C, Juárez-Rojas JG, Lanaspa MA, Johnson RJ, Sánchez-Lozada LG. Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. Biomolecules. 2019 10 11; 9(10).
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Ko J, Kang HJ, Kim DA, Kim MJ, Ryu ES, Lee S, Ryu JH, Roncal C, Johnson RJ, Kang DH. Uric acid induced the phenotype transition of vascular endothelial cells via induction of oxidative stress and glycocalyx shedding. FASEB J. 2019 12; 33(12):13334-13345.
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