 STAT4 Transcription Factor
"STAT4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important signaling molecule for differentiation in TH1 CELLS.
| Descriptor ID |
D050797
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| MeSH Number(s) |
D12.644.360.024.342.400 D12.776.157.057.186.400 D12.776.476.024.430.400 D12.776.930.840.400
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| Concept/Terms |
STAT4 Transcription Factor- STAT4 Transcription Factor
- Transcription Factor, STAT4
- Signal Transducer and Activator of Transcription 4
- STAT4 Protein
- Transcription Factor STAT4
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Below are MeSH descriptors whose meaning is more general than "STAT4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "STAT4 Transcription Factor".
This graph shows the total number of publications written about "STAT4 Transcription Factor" by people in this website by year, and whether "STAT4 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "STAT4 Transcription Factor" by people in Profiles.
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Patel ZH, Lu X, Miller D, Forney CR, Lee J, Lynch A, Schroeder C, Parks L, Magnusen AF, Chen X, Pujato M, Maddox A, Zoller EE, Namjou B, Brunner HI, Henrickson M, Huggins JL, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Pons-Estel BA, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarc?n GS, Martin J, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vil? LM, Petri M, Scofield RH, Kimberly RP, Edberg JC, Ramsey-Goldman R, Bang SY, Lee HS, Bae SC, Boackle SA, Cunninghame Graham D, Vyse TJ, Merrill JT, Niewold TB, Ainsworth HC, Silverman ED, Weisman MH, Wallace DJ, Raj P, Guthridge JM, Gaffney PM, Kelly JA, Alarc?n-Riquelme ME, Langefeld CD, Wakeland EK, Kaufman KM, Weirauch MT, Harley JB, Kottyan LC. A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. Hum Mol Genet. 2018 07 01; 27(13):2392-2404.
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Clark SE, Schmidt RL, McDermott DS, Lenz LL. A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection. Cell Rep. 2018 05 29; 23(9):2582-2594.
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Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug; 132(2):313-20.e15.
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Kelley JM, Hughes LB, Malik A, Danila MI, Edberg Y, Alarc?n GS, Conn DL, Jonas BL, Callahan LF, Smith EA, Brasington RD, Edberg JC, Kimberly RP, Moreland LW, Bridges SL. Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans. Ann Rheum Dis. 2010 Apr; 69(4):625-6.
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Matsubara S, Takeda K, Kodama T, Joetham A, Miyahara N, Koya T, Swasey CH, Okamoto M, Dakhama A, Gelfand EW. IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells. Am J Respir Cell Mol Biol. 2007 Mar; 36(3):324-32.
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